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Literature summary extracted from

  • Hallgren, N.K.; Busby, E.R.; Mommsen, T.P.
    Cell volume affects glycogen phosphorylase activity in fish hepatocytes (2003), J. Comp. Physiol. B, 173, 591-599.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.4.1.1 DMSO strong activation of enzyme in hepatocytes Ameiurus nebulosus
2.4.1.1 ethanol strong activation of enzyme in hepatocytes Ameiurus nebulosus
2.4.1.1 additional information activity is increased in hyperosmotic media by 7fold, activation is not influenced by EDTA or 8-bromo-Rp-cAMP Ameiurus nebulosus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.1 additional information activity is decreased in hyposmotic media Ameiurus nebulosus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.1.1 (1,4-alpha-D-glucosyl)n + phosphate Ameiurus nebulosus polysaccharide substrate is glycogen (1,4-alpha-D-glucosyl)n-1 + alpha-D-glucose 1-phosphate
-
 ?
2.4.1.1 additional information Ameiurus nebulosus the cell volume affects the activity in hepatocytes, thus the enzyme activity is a function of medium osmolarity, activity is increased in hyperosmotic media, overview ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.1 Ameiurus nebulosus
-
 brown bullhead catfish
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.4.1.1 additional information
-
 activities in media with different osmolarity Ameiurus nebulosus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.1 (1,4-alpha-D-glucosyl)n + phosphate polysaccharide substrate is glycogen Ameiurus nebulosus (1,4-alpha-D-glucosyl)n-1 + alpha-D-glucose 1-phosphate
-
 ?
2.4.1.1 (1,4-alpha-D-glucosyl)n + phosphate polysaccharide substrate is bovine liver glycogen Ameiurus nebulosus (1,4-alpha-D-glucosyl)n-1 + alpha-D-glucose 1-phosphate
-
 ?
2.4.1.1 additional information the cell volume affects the activity in hepatocytes, thus the enzyme activity is a function of medium osmolarity, activity is increased in hyperosmotic media, overview Ameiurus nebulosus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.1.1 glycogen phosphorylase
-
 Ameiurus nebulosus
2.4.1.1 GPase
-
 Ameiurus nebulosus
2.4.1.1 GPase a active enzyme form Ameiurus nebulosus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.4.1.1 21
-
 assay at Ameiurus nebulosus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.1.1 6.5
-
 assay at Ameiurus nebulosus