EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
1.21.99.3 | Se | selenoenzyme | Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.21.99.3 | additional information | Homo sapiens | the enzyme is the major physiological inactivator of thyroid hormone. The presence of the enzyme at maternal-fetal interfaces is consistent with its role in modulating the thyroid status of the human fetus and its expression in endometrium suggests that local regulation of thyroid status is important in implantation | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.21.99.3 | Homo sapiens | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.21.99.3 | colonic epithelium | fetal | Homo sapiens | - |
1.21.99.3 | cytotrophoblast | - |
Homo sapiens | - |
1.21.99.3 | decidua | - |
Homo sapiens | - |
1.21.99.3 | endothelium | of fetal vessels | Homo sapiens | - |
1.21.99.3 | respiratory epithelium | fetal | Homo sapiens | - |
1.21.99.3 | syncytiotrophoblast | - |
Homo sapiens | - |
1.21.99.3 | umbilical artery | - |
Homo sapiens | - |
1.21.99.3 | umbilical vein | - |
Homo sapiens | - |
1.21.99.3 | urinary tract | epithelium | Homo sapiens | - |
1.21.99.3 | uterine endometrium | of nonpregnant human uteri | Homo sapiens | - |
1.21.99.3 | uterus | endometrial gland | Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.21.99.3 | 3,3',5'-triido-L-thyronine + AH | - |
Homo sapiens | 3,3'-diiodothyronine + iodide + A + H+ | - |
? | |
1.21.99.3 | L-thyroxine + AH2 | - |
Homo sapiens | 3,3',5'-triido-L-thyronine + iodide + A + H+ | - |
? | |
1.21.99.3 | additional information | the enzyme is the major physiological inactivator of thyroid hormone. The presence of the enzyme at maternal-fetal interfaces is consistent with its role in modulating the thyroid status of the human fetus and its expression in endometrium suggests that local regulation of thyroid status is important in implantation | Homo sapiens | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.21.99.3 | type 3 iodothyronine deiodinase | - |
Homo sapiens |