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Literature summary extracted from
- Optimization of a process for the production of (R)-2-hydroxy-4-phenylbutyric acid - an intermediate for inhibitors of angiotonsin converting enzyme (1992), J. Biotechnol., 24, 315-327.
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 1.1.1.28 | synthesis | production of (R)-2-hydroxy-4-phenyl-butyric acid, which is a precursor for different ACE-inhibitors | Staphylococcus epidermidis |
General Stability
| EC Number | General Stability | Organism |
|---|---|---|
| 1.1.1.28 | for stabilization of the enzymes 0.15% mercaptoethanol and 1mM EDTA are added to the substrate solution. | Staphylococcus epidermidis |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.1.1.28 | Staphylococcus epidermidis | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.1.1.28 | 2-oxo-4-phenyl-butyric acid + NADH + H+ | - |
Staphylococcus epidermidis | (R)-2-hydroxy-4-phenyl-butyric acid + NAD+ | - |
? |  |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.28 | 30 | - |
- |
Staphylococcus epidermidis |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.28 | 8 | - |
- |
Staphylococcus epidermidis |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.1.1.28 | NADH | - |
Staphylococcus epidermidis | |
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Release 2023.1 (January 2023)
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