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Literature summary extracted from

  • Xu, A.; Lei, L.; Irvine, K.D.
    Regions of Drosophila Notch that contribute to ligand binding and the modulatory influence of Fringe (2005), J. Biol. Chem., 280, 30158-30165.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.1.222 Notch + UDP-D-GlcNAc Drosophila melanogaster Fringe and protein O-fucosyltransferase regulate Notch signaling via binding to cell surface Notch receptors, overview beta-D-glucosaminyl-Notch + UDP
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Organism

EC Number Organism UniProt Comment Textmining
2.4.1.222 Drosophila melanogaster
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-
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.222 Notch + UDP-D-GlcNAc Fringe and protein O-fucosyltransferase regulate Notch signaling via binding to cell surface Notch receptors, overview Drosophila melanogaster beta-D-glucosaminyl-Notch + UDP
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2.4.1.222 Notch + UDP-D-GlcNAc Notch protein is O-fucosylated at a serine or threonine residue in epidermal growth factor-like repeats, identification of glycosylation sites Drosophila melanogaster beta-D-glucosaminyl-Notch + UDP
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Synonyms

EC Number Synonyms Comment Organism
2.4.1.222 FNG
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Drosophila melanogaster