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Literature summary extracted from
- Heme oxygenase-2 is activated by calcium-calmodulin (2004), J. Biol. Chem., 279, 30927-30930.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.14.14.18 | Calmodulin | calcium-dependent binding to enzyme, 3fold increase in catalytic activity | Rattus norvegicus |  |
Protein Variants
| EC Number | Protein Variants | Comment | Organism |
|---|---|---|---|
| 1.14.14.18 | F66E | no activation by calmodulin | Rattus norvegicus |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.14.14.18 | calmidazolium chloride | inhibition of calmodulin-stimulation, 50% inhibition at 0.008 mM | Rattus norvegicus | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.14.14.18 | Rattus norvegicus | - |
isozyme HO2 | - |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.14.14.18 | Ho2 | - |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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