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Literature summary extracted from

  • Lin, S.; Shi, Q.; Nix, F.B.; Styblo, M.; Beck, M.A.; Herbin-Davis, K.M.; Hall, L.L.; Simeonsson, J.B.; Thomas, D.J.
    A novel S-adenosyl-L-methionine:arsenic(III) methyltransferase from rat liver cytosol (2002), J. Biol. Chem., 277, 10795-10803.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.1.1.137 cytosol
-
 Rattus norvegicus 5829
-

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.137 Homo sapiens Q9HBK9
-
-
2.1.1.137 Rattus norvegicus Q8VHT6
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.1.1.137
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.1.1.137 adrenal gland
-
 Rattus norvegicus
-
2.1.1.137 brain
-
 Rattus norvegicus
-
2.1.1.137 heart
-
 Rattus norvegicus
-
2.1.1.137 Hep-G2 cell mRNA is detected after 35 or 45 cycles of amplification Homo sapiens
-
2.1.1.137 kidney
-
 Rattus norvegicus
-
2.1.1.137 liver
-
 Rattus norvegicus
-
2.1.1.137 lung
-
 Rattus norvegicus
-
2.1.1.137 additional information not detected in UROtsa cells, an immortalized cell line derived from normal human urothelium, after 45 cycles of amplification Homo sapiens
-
2.1.1.137 urinary bladder
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.1.1.137 0.00149
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.137 S-adenosyl-L-methionine + arsenite
-
 Rattus norvegicus S-adenosyl-L-homocysteine + methylarsonate
-
 ?
2.1.1.137 S-adenosyl-L-methionine + methylarsonite
-
 Rattus norvegicus S-adenosyl-L-homocysteine + dimethylarsinate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.1.1.137 AdoMet:arsenic(III) methyltransferase
-
 Rattus norvegicus
2.1.1.137 Cyr19
-
 Rattus norvegicus
2.1.1.137 S-adenosyl-L-methionine:arsenic(III) methyltransferase
-
 Rattus norvegicus
2.1.1.137 S-adenosyl-L-methionine:arsenic(III) methyltransferase
-
 Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.1.1.137 9.5
-
-
 Rattus norvegicus

pH Range

EC Number pH Minimum pH Maximum Comment Organism
2.1.1.137 7.5 11 pH 7.5: about 40% of maximal activity, pH 11: about 35% of maximal activity Rattus norvegicus