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Literature summary extracted from

  • Wei, G.; Bai, X.; Sarkar, A.K.; Esko, J.D.
    Formation of HNK-1 determinants and the glycosaminoglycan tetrasaccharide linkage region by UDP-GlcUA:galactose beta1,3-glucuronosyltransferases (1999), J. Biol. Chem., 274, 7857-7864.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.4.1.135 transfection of a CHO cell mutant defective in GlcUAT-I with the hamster cDAN restores glycosaminoglycan assembly in vivo Cricetulus griseus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.1.135 0.67
-
 Galbeta1,3Galbeta-O-naphthalenemethanol pH 6.5, 37°C Cricetulus griseus
2.4.1.135 1.8
-
 Galbeta1,4GlcNAcbeta-O-naphthalenemethanol pH 6.5, 37°C Cricetulus griseus
2.4.1.135 2.9
-
 Galbeta1,3GlcNAcbeta-O-naphthalenemethanol pH 6.5, 37°C Cricetulus griseus
2.4.1.135 3.2
-
 Galbeta1,3GalNAcbeta-O-naphthalenemethanol pH 6.5, 37°C Cricetulus griseus

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.135 Cricetulus griseus Q9WU47
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.135 brain
-
 Cricetulus griseus
-
2.4.1.135 CHO cell
-
 Cricetulus griseus
-
2.4.1.135 heart
-
 Cricetulus griseus
-
2.4.1.135 kidney
-
 Cricetulus griseus
-
2.4.1.135 liver
-
 Cricetulus griseus
-
2.4.1.135 lung
-
 Cricetulus griseus
-
2.4.1.135 additional information barely detectable in spleen Cricetulus griseus
-
2.4.1.135 skeletal muscle
-
 Cricetulus griseus
-
2.4.1.135 testis
-
 Cricetulus griseus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.135 additional information no activity with Galalpha-O-p-nitrophenol, Galbeta-O-p-nitrophenol, Galalpha-O-a-naphthol, GalNAcalpha-O-p-nitrophenol, GalNAcbeta-O-p-nitrophenol Cricetulus griseus ?
-
 ?
2.4.1.135 UDP-alpha-D-glucuronate + Galbeta1,3Galbeta-O-naphthalenemethanol
-
 Cricetulus griseus ?
-
 ?
2.4.1.135 UDP-alpha-D-glucuronate + Galbeta1,3GalNAcbeta-O-naphthalenemethanol
-
 Cricetulus griseus ?
-
 ?
2.4.1.135 UDP-glucuronate + Galbeta(1-3)Gal-O-benzyl best substrate Cricetulus griseus UDP + ?
-
 ?
2.4.1.135 UDP-glucuronate + Galbeta(1-3)Gal-O-naphthalenemethanol best substrate Cricetulus griseus UDP + ?
-
 ?
2.4.1.135 UDP-glucuronate + Galbeta(1-3)GlcNAcalpha-O-benzyl
-
 Cricetulus griseus UDP + ?
-
 ?
2.4.1.135 UDP-glucuronate + Galbeta(1-3)GlcNAcalpha-O-naphthalenemethanol
-
 Cricetulus griseus UDP + ?
-
 ?
2.4.1.135 UDP-glucuronate + Galbeta(1-3)GlcNAcbeta-O-naphthalenemethanol
-
 Cricetulus griseus UDP + ?
-
 ?
2.4.1.135 UDP-glucuronate + Galbeta(1-4)Glcbeta-O-naphthalenemethanol
-
 Cricetulus griseus UDP + ?
-
 ?
2.4.1.135 UDP-glucuronate + Galbeta(1-4)GlcNAcbeta-O-naphthalenemethanol
-
 Cricetulus griseus UDP + ?
-
 ?
2.4.1.135 UDP-glucuronate + Galbeta-O-1-naphthol
-
 Cricetulus griseus UDP + GlcAbeta(1-3)Galbeta-O-1-naphthol
-
 ?
2.4.1.135 UDP-glucuronate + Galbeta-O-2-naphthol
-
 Cricetulus griseus UDP + GlcAbeta(1-3)Galbeta-O-2-naphthol
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.1.135 GlcUAT-I
-
 Cricetulus griseus