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Literature summary extracted from

  • Kossykh, V.G.; Lloyd, R.S.
    A DNA adenine methyltransferase of Escherichia coli that is cell cycle regulated and essential for viability (2004), J. Bacteriol., 186, 2061-2067.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.1.1.72 gene yhdJ or ccrM, chromosomally encoded, DNA sequence determination and analysis, overvexpression decreases bacterial growth by altering cell division, cells show aberant morphology Escherichia coli

Protein Variants

EC Number Protein Variants Comment Organism
2.1.1.72 additional information construction of a ccrM null mutant Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.1.1.72 S-adenosyl-L-methionine + DNA adenine Escherichia coli the enzyme is cell cycle regulated and essential for viability S-adenosyl-L-homocysteine + DNA 6-methylaminopurine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.72 Escherichia coli
-
 gene yhdJ or ccrM
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.1.1.72 recombinant enzyme from overexpression Escherichia coli

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.72 S-adenosyl-L-methionine + DNA adenine the enzyme is cell cycle regulated and essential for viability Escherichia coli S-adenosyl-L-homocysteine + DNA 6-methylaminopurine
-
 ?
2.1.1.72 S-adenosyl-L-methionine + DNA adenine enzyme methylates the first adenine in the sequence ATGCAT Escherichia coli S-adenosyl-L-homocysteine + DNA 6-methylaminopurine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.1.1.72 CcrM DNA adenine methyltransferase
-
 Escherichia coli
2.1.1.72 cell cycle-regulated methyltransferase
-
 Escherichia coli
2.1.1.72 DNA adenine methyltransferase
-
 Escherichia coli
2.1.1.72 DNA MTase
-
 Escherichia coli
2.1.1.72 M.EcoKCcrM
-
 Escherichia coli