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Literature summary extracted from

  • Herbette, S.; Lenne, C.; Leblanc, N.; Julien, J.L.; Drevet, J.R.; Roeckel-Drevet, P.
    Two GPX-like proteins from Lycopersicon esculentum and Helianthus annuus are antioxidant enzymes with phospholipid hydroperoxide glutathione peroxidase and thioredoxin peroxidase activities (2002), Eur. J. Biochem., 269, 2414-2420.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.11.1.12 expression in Escherichia coli Solanum lycopersicum

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.11.1.12 0.0121
-
phosphatidylcholine dilinoleoyl hydroperoxide
-
Solanum lycopersicum
1.11.1.12 0.0249
-
phosphatidylcholine dilinoleoyl hydroperoxide
-
Solanum lycopersicum
1.11.1.12 0.0393
-
linoleic acid hydroperoxide
-
Solanum lycopersicum
1.11.1.12 0.0827
-
linoleic acid hydroperoxide
-
Solanum lycopersicum
1.11.1.12 0.0953
-
tert-butyl hydroperoxide
-
Solanum lycopersicum
1.11.1.12 0.119
-
cumene hydroperoxide
-
Solanum lycopersicum
1.11.1.12 0.128
-
tert-butyl hydroperoxide
-
Solanum lycopersicum
1.11.1.12 608
-
cumene hydroperoxide
-
Solanum lycopersicum

Organism

EC Number Organism UniProt Comment Textmining
1.11.1.12 Solanum lycopersicum
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.11.1.12 GSH + cumene hydroperoxide
-
Solanum lycopersicum GSSG + ?
-
?
1.11.1.12 GSH + linoleic acid hydroperoxide
-
Solanum lycopersicum GSSG + ?
-
?
1.11.1.12 GSH + phosphatidylcholine dilinoleoyl hydroperoxide
-
Solanum lycopersicum GSSG + ?
-
?
1.11.1.12 GSH + tert-butyl hydroperoxide
-
Solanum lycopersicum GSSG + ?
-
?
1.11.1.12 additional information the enzyme shows phospholipid hydroperoxide glutathione peroxidase activity and thioredoxin peroxidase activity. Thioredoxin peroxidase activity is higher than phospholipid hydroperoxidase activity in terms of efficiency and substrate affinities. No activity with glutathione + H2O2 Solanum lycopersicum ?
-
?

Synonyms

EC Number Synonyms Comment Organism
1.11.1.12 GPXhs2
-
Solanum lycopersicum
1.11.1.12 GPXle1
-
Solanum lycopersicum