Literature summary extracted from

Ortiou, S.; Alberto, J.M.; Gueant, J.L.; Merten, M.
Homocysteine increases methionine synthase mRNA level in Caco-2 cells (2004), Cell. Physiol. Biochem., 14, 407-414.

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
2.1.1.13	5-methyltetrahydrofolate + L-homocysteine	Homo sapiens	homocysteine increases methionine synthase mRNA level	tetrahydrofolate + L-methionine	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.1.1.13	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.1.1.13	Caco-2 cell	adenocyrcinoma cell line	Homo sapiens	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.1.1.13	5-methyltetrahydrofolate + L-homocysteine	homocysteine increases methionine synthase mRNA level	Homo sapiens	tetrahydrofolate + L-methionine	-	?

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Release 2023.1 (January 2023)