Literature summary extracted from

Kershaw, N.J.; Mukherji, M.; MacKinnon, C.H.; Claridge, T.D.; Odell, B.; Wierzbicki, A.S.; Lloyd, M.D.; Schofield, C.J.
Studies on phytanoyl-CoA 2-hydroxylase and synthesis of phytanoyl-coenzyme A (2001), Bioorg. Med. Chem. Lett., 11, 2545-2548.

Metals/Ions

EC Number	Metals/Ions	Comment	Organism	Structure
1.14.11.18	Iron	required	Homo sapiens

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.14.11.18	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.14.11.18	liver	-	Homo sapiens	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.14.11.18	phytanoyl-CoA + 2-oxoglutarate + O2	3R and 3S epimers are hydroxylated with approximately equal efficiency. Both unprocessed proenzyme and mature form of PAHX are fully active	Homo sapiens	2-hydroxyphytanoyl-CoA + succinate + CO2	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
1.14.11.18	PAHX	-	Homo sapiens
1.14.11.18	phytanoyl-CoA 2-hydroxylase	-	Homo sapiens

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Release 2023.1 (January 2023)