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Literature summary extracted from

  • Dröse, S.; Zwicker, K.; Brandt, U.
    Full recovery of the NADH:ubiquinone activity of complex I (NADH:ubiquinone oxidoreductase) from Yarrowia lipolytica by the addition of phospholipids (2002), Biochim. Biophys. Acta, 1556, 65-72.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
7.1.1.2 asolectin activation by detergent solubilized asolectin Yarrowia lipolytica

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
7.1.1.2 mitochondrial membrane
-
 Yarrowia lipolytica 31966
-

Organism

EC Number Organism UniProt Comment Textmining
7.1.1.2 Yarrowia lipolytica
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
7.1.1.2 lipoprotein the phospholipid content varies between 26 and 66 mol phosphate per mol of complex in different batches. Complex 1 purified by affinity chromatography can be fully reactivated by returning phosphatidylcholine, phosphatidylethanolamine and cardiolipin, the phospholipids removed by the purification procedure Yarrowia lipolytica

Purification (Commentary)

EC Number Purification (Comment) Organism
7.1.1.2
-
 Yarrowia lipolytica

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.1.1.2 NADH + n-decylubiquinone + H+
-
 Yarrowia lipolytica NAD+ + n-decylubiquinol
-
 ?

Synonyms

EC Number Synonyms Comment Organism
7.1.1.2 complex 1
-
 Yarrowia lipolytica
7.1.1.2 NADH:ubiquinone oxidoreductase
-
 Yarrowia lipolytica

Cofactor

EC Number Cofactor Comment Organism Structure
7.1.1.2 additional information the enzyme contains only substoichiometric amounts of ubiquinone-9, 0.2-0.4 mol/mol Yarrowia lipolytica