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Literature summary extracted from
- Rabbit liver contains one major sterol 12alpha-hydroxylase with broad substrate specificity (1998), Biochim. Biophys. Acta, 1389, 150-154.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 1.14.14.139 | expression in COS cells | Oryctolagus cuniculus |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 1.14.14.139 | microsome | - |
Oryctolagus cuniculus | - |
- |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.14.14.139 | Oryctolagus cuniculus | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 1.14.14.139 | partially | Oryctolagus cuniculus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.14.14.139 | liver | - |
Oryctolagus cuniculus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.14.14.139 | 7alpha-hydroxycholest-4-en-3-one + NADPH + H+ + O2 | - |
Oryctolagus cuniculus | 7alpha,12alpha-dihydroxycholest-4-en-3-one + NADP+ + H2O | - |
? |  |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.14.14.139 | NADPH | - |
Oryctolagus cuniculus | |
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Release 2023.1 (January 2023)
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