Literature summary extracted from

Ikushiro, H.; Hayashi, H.; Kagamiyama, H.
Reactions of serine palmitoyltransferase with serine and molecular mechanisms of the actions of serine derivatives as inhibitors (2004), Biochemistry, 43, 1082-1092.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
2.3.1.50	expression in Escherichia coli	Sphingomonas paucimobilis

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.3.1.50	beta-chloro-L-alanine	irreversible	Sphingomonas paucimobilis
2.3.1.50	L-Cycloserine	irreversible	Sphingomonas paucimobilis
2.3.1.50	myriocin	-	Sphingomonas paucimobilis
2.3.1.50	sphingofungin B	-	Sphingomonas paucimobilis

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.3.1.50	Sphingomonas paucimobilis	-	EY2395	-
2.3.1.50	Sphingomonas paucimobilis EY2395	-	EY2395	-

Synonyms

EC Number	Synonyms	Comment	Organism
2.3.1.50	serine palmitoyltransferase	-	Sphingomonas paucimobilis
2.3.1.50	SPT	-	Sphingomonas paucimobilis

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
2.3.1.50	pyridoxal 5'-phosphate	-	Sphingomonas paucimobilis

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Release 2023.1 (January 2023)