EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
1.11.1.5 | H52L | with slower cyanide dissociation rate constant for the heme group with respect to the wild-type enzyme | Saccharomyces cerevisiae |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.11.1.5 | ferrocytochrome c + H2O2 | Saccharomyces cerevisiae | - |
ferricytochrome c + H2O | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.11.1.5 | Saccharomyces cerevisiae | - |
bakers´ yeast | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.11.1.5 | ferrocytochrome c + CN- | dominant binding pathway for H52L mutant, biphasic reaction | Saccharomyces cerevisiae | ? | - |
? | |
1.11.1.5 | ferrocytochrome c + H2O2 | - |
Saccharomyces cerevisiae | ferricytochrome c + H2O | - |
? | |
1.11.1.5 | ferrocytochrome c + HCN | dominant binding pathway for wild-type enzyme | Saccharomyces cerevisiae | ? | - |
? |
EC Number | pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|---|
1.11.1.5 | 4 | 8.6 | the association rate constant for the binding of cyanide to H52L mutant varies almost 4 orders of magnitude in this pH range. Above pH 8 cyanide binds more rapidly to H52L mutant than to wild-type enzyme | Saccharomyces cerevisiae |