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Literature summary extracted from

  • Guillou, H.; D'Andrea, S.; Rioux, V.; Jan, S.; Legrand, P.
    The surprising diversity of DELTA6-desaturase substrates (2004), Biochem. Soc. Trans., 32, 86-87.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.19.3 palmitic acid + AH2 + O2 Rattus norvegicus key enzyme required for numerous vital functions involving distinct polyunsaturated fatty acids and polyunsaturated fatty acid-derived bioactive lipids. It seems that the biological importance of DELTA6-desaturase activity should also be considered for its newly identified role in the control of the biosynthesis of a monoenoic fatty acid (C16:1 n-10), particularly in tissues with low DELTA9-desaturase activity hexadec-6-enoic acid + A + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.19.3 Rattus norvegicus
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 enzyme expressed in COS cells
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.19.3 palmitic acid + AH2 + O2
-
 Rattus norvegicus hexadec-6-enoic acid + A + H2O
-
 ?
1.14.19.3 palmitic acid + AH2 + O2 key enzyme required for numerous vital functions involving distinct polyunsaturated fatty acids and polyunsaturated fatty acid-derived bioactive lipids. It seems that the biological importance of DELTA6-desaturase activity should also be considered for its newly identified role in the control of the biosynthesis of a monoenoic fatty acid (C16:1 n-10), particularly in tissues with low DELTA9-desaturase activity Rattus norvegicus hexadec-6-enoic acid + A + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.19.3 DELTA6 desaturase
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 Rattus norvegicus
1.14.19.3 FADS2
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 Rattus norvegicus