EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
2.8.2.34 | 6-methylene-4-pregnene-3,20-dione | activates the hepatic enzyme in sham-operated and castrated male rats, effect is counteracted by 5alpha-dihydrotestosterone | Rattus norvegicus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.8.2.34 | 5alpha-dihydrotestosterone | inhibits the hepatic enzyme in sham-operated and castrated male rats, prevents activation by 6-methylene-4-pregnene-3,20-dione | Rattus norvegicus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.8.2.34 | Rattus norvegicus | - |
male sprague-dawley rats | - |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.8.2.34 | liver | - |
Rattus norvegicus | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
2.8.2.34 | 0.000012 | - |
castrated male rats with 5alpha-dihydrotestosterone, hepatic enzyme | Rattus norvegicus |
2.8.2.34 | 0.000017 | - |
sham-operated male rats with 5alpha-dihydrotestosterone, hepatic enzyme | Rattus norvegicus |
2.8.2.34 | 0.000019 | - |
sham-operated male rats with 5alpha-dihydrotestosterone and 6-methylene-4-pregnene-3,20-dione, hepatic enzyme | Rattus norvegicus |
2.8.2.34 | 0.000023 | - |
sham-operated male rats, hepatic enzyme | Rattus norvegicus |
2.8.2.34 | 0.000056 | - |
sham-operated male rats with 6-methylene-4-pregnene-3,20-dione, hepatic enzyme | Rattus norvegicus |
2.8.2.34 | 0.00006 | - |
castrated male rats, hepatic enzyme | Rattus norvegicus |
2.8.2.34 | 0.000083 | - |
castrated male rats with 6-methylene-4-pregnene-3,20-dione, hepatic enzyme | Rattus norvegicus |