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Literature summary extracted from

  • Kuhn, J.; Schnolzer, M.; Schon, S.; Muller, S.; Prante, C.; Gotting, C.; Kleesiek, K.
    Xylosyltransferase I acceptor properties of fibroblast growth factor and its fragment bFGF (1-24) (2005), Biochem. Biophys. Res. Commun., 333, 156-166.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.2.26 heparin non-competitive inhibitor using fragment(1-24) of human basic fibroblast growth factor as xylose acceptor Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.2.26 0.0208
-
 fragment(1-24) of human basic fibroblast growth factor native XT-I Homo sapiens
2.4.2.26 0.0223
-
 fragment(1-24) of human basic fibroblast growth factor recombinant XT-I Homo sapiens
2.4.2.26 0.0572
-
 human basic fibroblast growth factor native XT-I Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.2.26 extracellular
-
 Homo sapiens
-
-

Organism

EC Number Organism UniProt Comment Textmining
2.4.2.26 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.2.26 blood serum patients with osteoarthritis Homo sapiens
-
2.4.2.26 culture supernatant of JAR choriocarcinoma cells secrete six times more XT-I than the osteogenic sarcoma cell line SAOS-2 and 40times more XT-I than the fibroblast cell line hTERT-BJ1 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.2.26 UDP + fragment(1-24) of human basic fibroblast growth factor
-
 Homo sapiens UDP + ?
-
 ?
2.4.2.26 UDP + human basic fibroblast growth factor transfer of xylose to the serine residue of the G-S-G-motif in the amino terminal end of human basic fibroblast growth factor Homo sapiens UDP + ?
-
 ?
2.4.2.26 UDP-D-xylose + bikunin
-
 Homo sapiens UDP + D-xylosyl-bikunin
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.2.26 XT-I
-
 Homo sapiens