EC Number | Cloned (Comment) | Organism |
---|---|---|
2.3.1.51 | expression in Chineses hamster ovary cells | Homo sapiens |
EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
2.3.1.51 | 140delF | 34.8% of wild-type activity | Homo sapiens |
2.3.1.51 | 221delGT | 5% of wild-type activity | Homo sapiens |
2.3.1.51 | 252delMRT | 3.2% of wild-type activity | Homo sapiens |
2.3.1.51 | A239V | 90% of wild-type activity | Homo sapiens |
2.3.1.51 | D180fsX251 | 7.7% of wild-type activity | Homo sapiens |
2.3.1.51 | G136R | 40.3% of wild-type activity | Homo sapiens |
2.3.1.51 | L228P | 23.7% of wild-type activity | Homo sapiens |
2.3.1.51 | R68X | 14.2% of wild-type activity | Homo sapiens |
2.3.1.51 | V167fsX228 | 14.9% of wild-type activity | Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.51 | acyl-CoA + 1-acyl-sn-glycerol 3-phosphate | Homo sapiens | reduction in AGPAT2 activity underlies the loss of adipose tissue in congenital generalized lipodystrophy | CoA + 1,2-diacyl-sn-glycerol 3-phosphate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.3.1.51 | Homo sapiens | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.51 | acyl-CoA + 1-acyl-sn-glycerol 3-phosphate | reduction in AGPAT2 activity underlies the loss of adipose tissue in congenital generalized lipodystrophy | Homo sapiens | CoA + 1,2-diacyl-sn-glycerol 3-phosphate | - |
? | |
2.3.1.51 | arachidonoyl-CoA + 1-oleoyl-glycerol-3-phosphate | - |
Homo sapiens | 1-oleoyl-2-arachidonoyl-glycerol-3-phosphate + CoA | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.3.1.51 | 1-acylglycerol-3-phosphate-O-acyltransferase 2 | - |
Homo sapiens |
2.3.1.51 | AGPAT2 | - |
Homo sapiens |