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Literature summary extracted from

  • Selvakumar, P.; Lakshmikuttyamma, A.; Lawman, Z.; Bonham, K.; Dimmock, J.R.; Sharma, R.K.
    Expression of methionine aminopeptidase 2,N-myristoyltransferase, and N-myristoyltransferase inhibitor protein 71 in HT29 (2004), Biochem. Biophys. Res. Commun., 322, 1012-1017.
    View publication on PubMed

Application

EC Number Application Comment Organism
3.4.11.18 medicine in colon cancer cell line HT-29, expression of enzyme is inversely correlated to cell density Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.97 N-myristoyltransferase inhibitor protein 71
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.97 myristoyl-CoA + glycylpeptide Homo sapiens the enzyme plays a major role in the process of myristoylation of oncoproteins including the c-src family N-myristoylglycylpeptide + CoA
-
 ?
3.4.11.18 additional information Homo sapiens together with N-myristoyltransferase, enzyme plays a major role in the process of myristoylation of oncoproteins including the c-src family ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.97 Homo sapiens
-
-
-
3.4.11.18 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.97 HT-29 cell
-
 Homo sapiens
-
3.4.11.18 carcinoma cell
-
 Homo sapiens
-
3.4.11.18 colon colon cancer cell Homo sapiens
-
3.4.11.18 HT-29 cell colon cancer cell line, expression of enzyme is inversely correlated to cell density Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.97 myristoyl-CoA + glycylpeptide the enzyme plays a major role in the process of myristoylation of oncoproteins including the c-src family Homo sapiens N-myristoylglycylpeptide + CoA
-
 ?
3.4.11.18 L-Met-N-myristoyltransferase + H2O
-
 Homo sapiens L-Met + N-myristoyltransferase
-
 ?
3.4.11.18 additional information together with N-myristoyltransferase, enzyme plays a major role in the process of myristoylation of oncoproteins including the c-src family Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.97 N-myristoyltransferase
-
 Homo sapiens
2.3.1.97 NMT
-
 Homo sapiens