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Literature summary extracted from

  • Chambers, K.; Brown, W.J.
    Characterization of a novel CI-976-sensitive lysophospholipid acyltransferase that is associated with the Golgi complex (2004), Biochem. Biophys. Res. Commun., 313, 681-686.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.23 2,2-dimethyl-N-(2,4,6-trimethoxyphenyl)-dodecanamide
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.23 Golgi membrane associated with, catalytic domain of the enzyme is exposed to the cytosol rather than to lumen of the Golgi cisternae Rattus norvegicus 139
-

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.23 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.23 brain
-
 Rattus norvegicus
-
2.3.1.23 heart
-
 Rattus norvegicus
-
2.3.1.23 intestine very low activity Rattus norvegicus
-
2.3.1.23 kidney low activity Rattus norvegicus
-
2.3.1.23 liver
-
 Rattus norvegicus
-
2.3.1.23 lung
-
 Rattus norvegicus
-
2.3.1.23 muscle
-
 Rattus norvegicus
-
2.3.1.23 pancreas very low activity Rattus norvegicus
-
2.3.1.23 spleen
-
 Rattus norvegicus
-
2.3.1.23 testis
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.23 palmitoyl-CoA + lysophosphatidylcholine
-
 Rattus norvegicus CoA + ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.23 LPAT
-
 Rattus norvegicus
2.3.1.23 lysophospholipid acyltransferase
-
 Rattus norvegicus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.23 7 8 Golgi-associated enzyme Rattus norvegicus

pH Range

EC Number pH Minimum pH Maximum Comment Organism
2.3.1.23 6 10 pH 6.0: about 55% of maximal activity, pH 10.0: about 80% of maximal activity, Golgi-associated enzyme Rattus norvegicus