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Literature summary extracted from

  • Khairnar, N.P.; Misra, H.S.; Apte, S.K.
    Pyrroloquinoline-quinone synthesized in Escherichia coli by pyrroloquinoline-quinone synthase of Deinococcus radiodurans plays a role beyond mineral phosphate solubilization (2003), Biochem. Biophys. Res. Commun., 312, 303-308.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.3.3.11 expressed in Escherichia coli BL21(DE3)pLysS, complements the mineral phosphate solubilization phenotype Deinococcus radiodurans

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.3.3.11 42000
-
 x * 42000, SDS-PAGE Deinococcus radiodurans

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.3.3.11 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic acid + O2 Deinococcus radiodurans synthesis of the pyrroloquinoline quinone (PQQ), that serves as prosthetic group for many bacterial enzymes, PQQ might also be involved in the protection against reactive oxygen species during growth under stress conditions 4,5-dioxo-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate + H2O2 + H2O the product is pyrroloquinoline quinone (PQQ) ?
1.3.3.11 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic acid + O2 Deinococcus radiodurans KR1 synthesis of the pyrroloquinoline quinone (PQQ), that serves as prosthetic group for many bacterial enzymes, PQQ might also be involved in the protection against reactive oxygen species during growth under stress conditions 4,5-dioxo-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate + H2O2 + H2O the product is pyrroloquinoline quinone (PQQ) ?

Organism

EC Number Organism UniProt Comment Textmining
1.3.3.11 Deinococcus radiodurans
-
 extremely radioresitant
-
1.3.3.11 Deinococcus radiodurans KR1
-
 extremely radioresitant
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.3.11 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic acid + O2
-
 Deinococcus radiodurans 4,5-dioxo-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate + H2O2 + H2O the product is pyrroloquinoline quinone (PQQ) ?
1.3.3.11 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic acid + O2 synthesis of the pyrroloquinoline quinone (PQQ), that serves as prosthetic group for many bacterial enzymes, PQQ might also be involved in the protection against reactive oxygen species during growth under stress conditions Deinococcus radiodurans 4,5-dioxo-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate + H2O2 + H2O the product is pyrroloquinoline quinone (PQQ) ?
1.3.3.11 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic acid + O2
-
 Deinococcus radiodurans KR1 4,5-dioxo-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate + H2O2 + H2O the product is pyrroloquinoline quinone (PQQ) ?
1.3.3.11 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic acid + O2 synthesis of the pyrroloquinoline quinone (PQQ), that serves as prosthetic group for many bacterial enzymes, PQQ might also be involved in the protection against reactive oxygen species during growth under stress conditions Deinococcus radiodurans KR1 4,5-dioxo-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate + H2O2 + H2O the product is pyrroloquinoline quinone (PQQ) ?

Subunits

EC Number Subunits Comment Organism
1.3.3.11 ? x * 42000, SDS-PAGE Deinococcus radiodurans

Synonyms

EC Number Synonyms Comment Organism
1.3.3.11 PqqC
-
 Deinococcus radiodurans