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Literature summary extracted from

  • Hayashi, Y.; Horibata, Y.; Sakaguchi, K.; Okino, N.; Ito, M.
    A sensitive and reproducible assay to measure the activity of glucosylceramide synthase and lactosylceramide synthase using HPLC and fluorescent substrates (2005), Anal. Biochem., 345, 181-186.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.1.80 UDP-glucose + ceramide Cricetulus griseus key enzyme in the synthesis of major glycosphingolipids in vertebrates UDP + glucosylceramide glucosylceramide is the core structure of major glycosphingolipids ?
2.4.1.80 UDP-glucose + ceramide Danio rerio key enzyme in the synthesis of major glycosphingolipids in vertebrates UDP + glucosylceramide glucosylceramide is the core structure of major glycosphingolipids ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.80 Cricetulus griseus
-
-
-
2.4.1.80 Danio rerio
-
 zebrafish
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.80 CHOP cell ovary cells expressing the LT antigen Cricetulus griseus
-
2.4.1.80 embryo
-
 Danio rerio
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.4.1.80 additional information
-
 assay method development Cricetulus griseus
2.4.1.80 additional information
-
 assay method development Danio rerio

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.80 UDP-glucose + 6-([(N-7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino]caproyl)sphingosine synthetic fluorescent substrate in liposomes for assay method development Cricetulus griseus UDP + N-(6-((4-nitrobenz-2-oxa-1,3-diazol-7-yl)amino)caproyl)-O1-D-glucosyl-sphingosine
-
 ?
2.4.1.80 UDP-glucose + 6-([(N-7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino]caproyl)sphingosine synthetic fluorescent substrate in liposomes for assay method development Danio rerio UDP + N-(6-((4-nitrobenz-2-oxa-1,3-diazol-7-yl)amino)caproyl)-O1-D-glucosyl-sphingosine
-
 ?
2.4.1.80 UDP-glucose + ceramide
-
 Cricetulus griseus UDP + glucosylceramide
-
 ?
2.4.1.80 UDP-glucose + ceramide
-
 Danio rerio UDP + glucosylceramide
-
 ?
2.4.1.80 UDP-glucose + ceramide key enzyme in the synthesis of major glycosphingolipids in vertebrates Cricetulus griseus UDP + glucosylceramide glucosylceramide is the core structure of major glycosphingolipids ?
2.4.1.80 UDP-glucose + ceramide key enzyme in the synthesis of major glycosphingolipids in vertebrates Danio rerio UDP + glucosylceramide glucosylceramide is the core structure of major glycosphingolipids ?

Synonyms

EC Number Synonyms Comment Organism
2.4.1.80 GlcT
-
 Cricetulus griseus
2.4.1.80 GlcT
-
 Danio rerio
2.4.1.80 glucosylceramide synthase
-
 Cricetulus griseus
2.4.1.80 glucosylceramide synthase
-
 Danio rerio