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Literature summary extracted from
- 1,3-Propanediol oxidoreductase production with Klebsiella pneumoniae DSM2026 (2003), World J. Microbiol. Biotechnol., 19, 659-663.
No PubMed abstract available
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.1.1.202 | glycerol | at concentrations around 16 g/l, regulation, overview | Klebsiella pneumoniae |  |
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 1.1.1.202 | synthesis | Klebsiella pneumoniae is used for production of 1,3-propanediol by the enzyme which is utilized in plastic industry | Klebsiella pneumoniae |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.1.1.202 | glycerol | at high concentration above 40 g/l, overview | Klebsiella pneumoniae | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.1.1.202 | propane-1,3-diol + NAD+ | Klebsiella pneumoniae | key enzyme of the 1,3-propanediol production pathway, high enzyme synthesis and activity in the anaerobic growth phase with increased use of glycerol | 3-hydroxypropanal + NADH | - |
? | |
| 1.1.1.202 | propane-1,3-diol + NAD+ | Klebsiella pneumoniae DSM 2026 | key enzyme of the 1,3-propanediol production pathway, high enzyme synthesis and activity in the anaerobic growth phase with increased use of glycerol | 3-hydroxypropanal + NADH | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.1.1.202 | Klebsiella pneumoniae | - |
DSM2026 | - |
| 1.1.1.202 | Klebsiella pneumoniae DSM 2026 | - |
DSM2026 | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.1.1.202 | propane-1,3-diol + NAD+ | - |
Klebsiella pneumoniae | 3-hydroxypropanal + NADH | - |
r | |
| 1.1.1.202 | propane-1,3-diol + NAD+ | key enzyme of the 1,3-propanediol production pathway, high enzyme synthesis and activity in the anaerobic growth phase with increased use of glycerol | Klebsiella pneumoniae | 3-hydroxypropanal + NADH | - |
? | |
| 1.1.1.202 | propane-1,3-diol + NAD+ | - |
Klebsiella pneumoniae DSM 2026 | 3-hydroxypropanal + NADH | - |
r | |
| 1.1.1.202 | propane-1,3-diol + NAD+ | key enzyme of the 1,3-propanediol production pathway, high enzyme synthesis and activity in the anaerobic growth phase with increased use of glycerol | Klebsiella pneumoniae DSM 2026 | 3-hydroxypropanal + NADH | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.1.1.202 | 1,3-propanediol oxidoreductase | - |
Klebsiella pneumoniae |
| 1.1.1.202 | 1,3-propanediol-oxidoreductase | - |
Klebsiella pneumoniae |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.202 | 25 | - |
assay at | Klebsiella pneumoniae |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.202 | 9 | - |
assay at | Klebsiella pneumoniae |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.1.1.202 | NAD+ | - |
Klebsiella pneumoniae | |
| 1.1.1.202 | NADH | - |
Klebsiella pneumoniae | |
Ki Value [mM]
| EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 1.1.1.202 | 12.09 | - |
glycerol | pH 9.0, 25°C | Klebsiella pneumoniae | |
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