Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Cohen, P.T.W
    Overview of protein serine/threonine phosphatases (2004), Topics in Current Genetics (Arino, J. , Alexander, D. R. Eds. ) Springer, 5, 1-20.
No PubMed abstract available

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.3.16 Calmodulin
-
 Homo sapiens
3.1.3.16 TFIIF a transcription factor that binds to the C-terminal domain Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.3.16 cyclophilin
-
 Homo sapiens
3.1.3.16 cyclosporin
-
 Homo sapiens
3.1.3.16 microcystin
-
 Homo sapiens
3.1.3.16 okadaic acid
-
 Homo sapiens
3.1.3.16 Protein phosphatase inhibitor-1
-
 Homo sapiens
3.1.3.16 protein phosphatase inhibitor-2
-
 Homo sapiens
3.1.3.16 tautomycin
-
 Homo sapiens

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.3.16 Ca2+
-
 Homo sapiens
3.1.3.16 Mg2+ essential for activity Homo sapiens
3.1.3.16 Mn2+
-
 Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.3.16 57000
-
 1 * 57000, with fused TPR domain Homo sapiens
3.1.3.16 76000
-
 x * 76000 Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.3.16 phospho-Cdk2 + H2O Homo sapiens
-
 Cdk6 + phosphate
-
 ?
3.1.3.16 phospho-Cdk6 + H2O Homo sapiens
-
 Cdk6 + phosphate
-
 ?
3.1.3.16 phospho-MKK + H2O Homo sapiens
-
 MKK + phosphate
-
 ?
3.1.3.16 phospho-TAK1 + H2O Homo sapiens
-
 TAK1 + phosphate
-
 ?
3.1.3.16 phosphorylated ILK1 + H2O Homo sapiens negative regulation of Wnt signaling ILK1 + phosphate
-
 ?
3.1.3.16 phosphorylated p38 + H2O Homo sapiens
-
 p38 + phosphate
-
 ?
3.1.3.16 phosphorylated rhodopsin + H2O Homo sapiens
-
 rhodopsin + phosphate
-
 ?
3.1.3.16 phosphorylated RNA polymerase II + H2O Homo sapiens
-
 RNA polymerase II + phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.16 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.3.16 brain
-
 Homo sapiens
-
3.1.3.16 retina
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.16 phospho-Cdk2 + H2O
-
 Homo sapiens Cdk6 + phosphate
-
 ?
3.1.3.16 phospho-Cdk6 + H2O
-
 Homo sapiens Cdk6 + phosphate
-
 ?
3.1.3.16 phospho-MKK + H2O
-
 Homo sapiens MKK + phosphate
-
 ?
3.1.3.16 phospho-TAK1 + H2O
-
 Homo sapiens TAK1 + phosphate
-
 ?
3.1.3.16 phosphorylated ILK1 + H2O negative regulation of Wnt signaling Homo sapiens ILK1 + phosphate
-
 ?
3.1.3.16 phosphorylated ILK1 + H2O Wip1 Homo sapiens ILK1 + phosphate
-
 ?
3.1.3.16 phosphorylated p38 + H2O
-
 Homo sapiens p38 + phosphate
-
 ?
3.1.3.16 phosphorylated rhodopsin + H2O
-
 Homo sapiens rhodopsin + phosphate
-
 ?
3.1.3.16 phosphorylated RNA polymerase II + H2O
-
 Homo sapiens RNA polymerase II + phosphate
-
 ?
3.1.3.16 phosphorylated RNA polymerase II + H2O dephosphorylation of the carboxyterminal domain Homo sapiens RNA polymerase II + phosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.3.16 ? x * 76000 Homo sapiens
3.1.3.16 heterodimer
-
 Homo sapiens
3.1.3.16 heterodimer and higher molecular mass structures Homo sapiens
3.1.3.16 heterodimer with fused calmodulin binding and autoinhibitory domains Homo sapiens
3.1.3.16 heterotrimer
-
 Homo sapiens
3.1.3.16 monomer
-
 Homo sapiens
3.1.3.16 monomer 1 * 57000, with fused TPR domain Homo sapiens
3.1.3.16 monomer fused collagen homology domain Homo sapiens
3.1.3.16 monomer fused PIX binding domain Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
3.1.3.16 CALNA
-
 Homo sapiens
3.1.3.16 CALNB
-
 Homo sapiens
3.1.3.16 CaMIIKPase
-
 Homo sapiens
3.1.3.16 CNAalpha
-
 Homo sapiens
3.1.3.16 CNAbeta
-
 Homo sapiens
3.1.3.16 CNAgamma
-
 Homo sapiens
3.1.3.16 Fcp1
-
 Homo sapiens
3.1.3.16 FIN13
-
 Homo sapiens
3.1.3.16 hFEM2
-
 Homo sapiens
3.1.3.16 ILKAP
-
 Homo sapiens
3.1.3.16 NERPP-2C
-
 Homo sapiens
3.1.3.16 PDP1
-
 Homo sapiens
3.1.3.16 PDP2
-
 Homo sapiens
3.1.3.16 POPX1
-
 Homo sapiens
3.1.3.16 POPX2
-
 Homo sapiens
3.1.3.16 PP1alpha
-
 Homo sapiens
3.1.3.16 PP1beta
-
 Homo sapiens
3.1.3.16 PP1cgamma
-
 Homo sapiens
3.1.3.16 PP1delta
-
 Homo sapiens
3.1.3.16 PP1gamma
-
 Homo sapiens
3.1.3.16 PP2Aalpha
-
 Homo sapiens
3.1.3.16 PP2Abeta
-
 Homo sapiens
3.1.3.16 PP2Acalpha
-
 Homo sapiens
3.1.3.16 PP2Acbeta
-
 Homo sapiens
3.1.3.16 PP2Balpha
-
 Homo sapiens
3.1.3.16 PP2Bbeta
-
 Homo sapiens
3.1.3.16 PP2Bgamma
-
 Homo sapiens
3.1.3.16 PP2Calpha
-
 Homo sapiens
3.1.3.16 PP2Cbeta
-
 Homo sapiens
3.1.3.16 PP2Cdelta
-
 Homo sapiens
3.1.3.16 PP2Cgamma
-
 Homo sapiens
3.1.3.16 Pp4
-
 Homo sapiens
3.1.3.16 PP5
-
 Homo sapiens
3.1.3.16 PP6
-
 Homo sapiens
3.1.3.16 PPEF1
-
 Homo sapiens
3.1.3.16 PPEF2
-
 Homo sapiens
3.1.3.16 Ppp1calpha
-
 Homo sapiens
3.1.3.16 Ppp1cbeta
-
 Homo sapiens
3.1.3.16 Ppp1cgamma
-
 Homo sapiens
3.1.3.16 Ppp2calpha
-
 Homo sapiens
3.1.3.16 Ppp2cbeta
-
 Homo sapiens
3.1.3.16 Ppp3calpha
-
 Homo sapiens
3.1.3.16 Ppp3cbeta
-
 Homo sapiens
3.1.3.16 Ppp3cgamma
-
 Homo sapiens
3.1.3.16 Ppp4c
-
 Homo sapiens
3.1.3.16 Ppp5c
-
 Homo sapiens
3.1.3.16 Ppp6c
-
 Homo sapiens
3.1.3.16 Ppp7calpha
-
 Homo sapiens
3.1.3.16 Ppp7cbeta
-
 Homo sapiens
3.1.3.16 PPT
-
 Homo sapiens
3.1.3.16 PPX
-
 Homo sapiens
3.1.3.16 Wip1
-
 Homo sapiens