EC Number | Crystallization (Comment) | Organism |
---|---|---|
3.5.1.88 | vapour diffusion method. Crystallization of protein and protein-inhibitor complexes with N-formyl-H-hydroxy-3-phenylpropylamine, N-hydroxy-N-[3-(6-methyl pyridine-2-yl)propyl] formamide or N-formyl-N-hydroxy-2-(3-benzoylphenoxy)ethylamine | Staphylococcus aureus |
3.5.1.88 | vapour diffusion method. Crystallization of protein and protein-inhibitor complexes with N-formyl-H-hydroxy-3-phenylpropylamine, N-hydroxy-N-[3-(6-methyl pyridine-2-yl)propyl] formamide or N-formyl-N-hydroxy-2-(3-benzoylphenoxy)ethylamine | Haemophilus influenzae |
3.5.1.88 | vapour diffusion method. Crystallization of protein and protein-inhibitor complexes with N-formyl-H-hydroxy-3-phenylpropylamine, N-hydroxy-N-[3-(6-methyl pyridine-2-yl)propyl] formamide or N-formyl-N-hydroxy-2-(3-benzoylphenoxy)ethylamine | Escherichia coli |
3.5.1.88 | vapour diffusion method. Crystallization of protein and protein-inhibitor complexes with N-formyl-H-hydroxy-3-phenylpropylamine, N-hydroxy-N-[3-(6-methyl pyridine-2-yl)propyl] formamide or N-formyl-N-hydroxy-2-(3-benzoylphenoxy)ethylamine | Streptococcus pneumoniae |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.5.1.88 | N-formyl-N-hydroxy-2-(3-benzoylphenoxy)ethylamine | i.e. SB 543668, IC50: 0.00115 mM | Escherichia coli | |
3.5.1.88 | N-formyl-N-hydroxy-2-(3-benzoylphenoxy)ethylamine | i.e. SB 543668, IC50: 0.00032 mM | Haemophilus influenzae | |
3.5.1.88 | N-formyl-N-hydroxy-2-(3-benzoylphenoxy)ethylamine | i.e. SB 543668, IC50: 0.0022 mM | Staphylococcus aureus | |
3.5.1.88 | N-formyl-N-hydroxy-2-(3-benzoylphenoxy)ethylamine | i.e. SB 543668, IC50: 0.0039 mM | Streptococcus pneumoniae | |
3.5.1.88 | N-formyl-N-hydroxy-3-phenylpropylamine | i.e. SB 485345, IC50: 0.00016 mM | Escherichia coli | |
3.5.1.88 | N-formyl-N-hydroxy-3-phenylpropylamine | i.e. SB 485345, IC50: 0.00015 mM | Haemophilus influenzae | |
3.5.1.88 | N-formyl-N-hydroxy-3-phenylpropylamine | i.e. SB 485345, IC50: 0.00025 mM | Staphylococcus aureus | |
3.5.1.88 | N-formyl-N-hydroxy-3-phenylpropylamine | i.e. SB 485345, IC50: 0.0004 mM | Streptococcus pneumoniae | |
3.5.1.88 | N-hydroxy-N-[3-(6-methylpyridine-2-yl)propyl]formamide | i.e. SB 505684, IC50: 0.0028 mM | Escherichia coli | |
3.5.1.88 | N-hydroxy-N-[3-(6-methylpyridine-2-yl)propyl]formamide | i.e. SB 505684, IC50: 0.00104 mM | Haemophilus influenzae | |
3.5.1.88 | N-hydroxy-N-[3-(6-methylpyridine-2-yl)propyl]formamide | i.e. SB 505684, IC50: 0.00109 mM | Staphylococcus aureus | |
3.5.1.88 | N-hydroxy-N-[3-(6-methylpyridine-2-yl)propyl]formamide | i.e. SB 505684, IC50: 0.0022 mM | Streptococcus pneumoniae |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.5.1.88 | 2.6 | - |
formyl-Met-Ala-Ser | pH 7.6, 25°C | Staphylococcus aureus | |
3.5.1.88 | 4 | - |
formyl-Met-Ala-Ser | pH 7.6, 25°C | Streptococcus pneumoniae | |
3.5.1.88 | 4.8 | - |
formyl-Met-Ala-Ser | pH 7.6, 25°C | Haemophilus influenzae | |
3.5.1.88 | 9.1 | - |
formyl-Met-Ala-Ser | pH 7.6, 25°C | Escherichia coli |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.5.1.88 | Escherichia coli | - |
- |
- |
3.5.1.88 | Haemophilus influenzae | - |
- |
- |
3.5.1.88 | Staphylococcus aureus | - |
- |
- |
3.5.1.88 | Streptococcus pneumoniae | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.5.1.88 | formyl-Met-Ala-Ser + H2O | - |
Staphylococcus aureus | formate + Met-Ala-Ser | - |
? | |
3.5.1.88 | formyl-Met-Ala-Ser + H2O | - |
Haemophilus influenzae | formate + Met-Ala-Ser | - |
? | |
3.5.1.88 | formyl-Met-Ala-Ser + H2O | - |
Escherichia coli | formate + Met-Ala-Ser | - |
? | |
3.5.1.88 | formyl-Met-Ala-Ser + H2O | - |
Streptococcus pneumoniae | formate + Met-Ala-Ser | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.5.1.88 | - |
Staphylococcus aureus | |
3.5.1.88 | - |
Haemophilus influenzae | |
3.5.1.88 | - |
Escherichia coli | |
3.5.1.88 | - |
Streptococcus pneumoniae |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.5.1.88 | 103 | - |
formyl-Met-Ala-Ser | pH7.6, 25°C | Escherichia coli | |
3.5.1.88 | 152 | - |
formyl-Met-Ala-Ser | pH7.6, 25°C | Staphylococcus aureus | |
3.5.1.88 | 322 | - |
formyl-Met-Ala-Ser | pH7.6, 25°C | Haemophilus influenzae | |
3.5.1.88 | 332 | - |
formyl-Met-Ala-Ser | pH7.6, 25°C | Streptococcus pneumoniae |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
3.5.1.88 | 0.00015 | - |
i.e. SB 485345, IC50: 0.00015 mM | Haemophilus influenzae | N-formyl-N-hydroxy-3-phenylpropylamine | |
3.5.1.88 | 0.00016 | - |
i.e. SB 485345, IC50: 0.00016 mM | Escherichia coli | N-formyl-N-hydroxy-3-phenylpropylamine | |
3.5.1.88 | 0.00025 | - |
i.e. SB 485345, IC50: 0.00025 mM | Staphylococcus aureus | N-formyl-N-hydroxy-3-phenylpropylamine | |
3.5.1.88 | 0.00032 | - |
i.e. SB 543668, IC50: 0.00032 mM | Haemophilus influenzae | N-formyl-N-hydroxy-2-(3-benzoylphenoxy)ethylamine | |
3.5.1.88 | 0.00104 | - |
i.e. SB 505684, IC50: 0.00104 mM | Haemophilus influenzae | N-hydroxy-N-[3-(6-methylpyridine-2-yl)propyl]formamide | |
3.5.1.88 | 0.00109 | - |
i.e. SB 505684, IC50: 0.00109 mM | Staphylococcus aureus | N-hydroxy-N-[3-(6-methylpyridine-2-yl)propyl]formamide | |
3.5.1.88 | 0.00115 | - |
i.e. SB 543668, IC50: 0.00115 mM | Escherichia coli | N-formyl-N-hydroxy-2-(3-benzoylphenoxy)ethylamine | |
3.5.1.88 | 0.0022 | - |
i.e. SB 543668, IC50: 0.0022 mM | Staphylococcus aureus | N-formyl-N-hydroxy-2-(3-benzoylphenoxy)ethylamine | |
3.5.1.88 | 0.0028 | - |
i.e. SB 505684, IC50: 0.0028 mM | Escherichia coli | N-hydroxy-N-[3-(6-methylpyridine-2-yl)propyl]formamide |