BRENDA - Enzyme Database

Structure and function of glutamyl-tRNA reductase, the first enzyme of tetrapyrrole biosynthesis in plants and prokaryotes

Schubert, W.D.; Moser, J.; Schauer, S.; Heinz, D.W.; Jahn, D.; Photosyn. Res. 74, 205-215 (c) (2002)

Data extracted from this reference:

Crystallization (Commentary)
EC Number
Crystallization
Organism
1.2.1.70
crystallized in presence of glutamycin, the structure is solved by the multiple isomorphous replacement method using three heavy atom derivatives. The structure is subsequently refined at a resolution of 1.95 A
Methanopyrus kandleri
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
1.2.1.70
L-glutamyl-tRNAGlu + NADPH + H+
Methanopyrus kandleri
the enzyme catalyzes the initial step of tetrapyrrole biosynthesis
L-glutamate 1-semialdehyde + NADP+ + tRNAGlu
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
1.2.1.70
Methanopyrus kandleri
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.2.1.70
L-glutamyl-tRNAGlu + NADPH + H+
-
656906
Methanopyrus kandleri
L-glutamate 1-semialdehyde + NADP+ + tRNAGlu
-
-
-
?
1.2.1.70
L-glutamyl-tRNAGlu + NADPH + H+
the enzyme catalyzes the initial step of tetrapyrrole biosynthesis
656906
Methanopyrus kandleri
L-glutamate 1-semialdehyde + NADP+ + tRNAGlu
-
-
-
?
Cofactor
EC Number
Cofactor
Commentary
Organism
Structure
1.2.1.70
NADPH
-
Methanopyrus kandleri
Cofactor (protein specific)
EC Number
Cofactor
Commentary
Organism
Structure
1.2.1.70
NADPH
-
Methanopyrus kandleri
Crystallization (Commentary) (protein specific)
EC Number
Crystallization
Organism
1.2.1.70
crystallized in presence of glutamycin, the structure is solved by the multiple isomorphous replacement method using three heavy atom derivatives. The structure is subsequently refined at a resolution of 1.95 A
Methanopyrus kandleri
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
1.2.1.70
L-glutamyl-tRNAGlu + NADPH + H+
Methanopyrus kandleri
the enzyme catalyzes the initial step of tetrapyrrole biosynthesis
L-glutamate 1-semialdehyde + NADP+ + tRNAGlu
-
-
?
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.2.1.70
L-glutamyl-tRNAGlu + NADPH + H+
-
656906
Methanopyrus kandleri
L-glutamate 1-semialdehyde + NADP+ + tRNAGlu
-
-
-
?
1.2.1.70
L-glutamyl-tRNAGlu + NADPH + H+
the enzyme catalyzes the initial step of tetrapyrrole biosynthesis
656906
Methanopyrus kandleri
L-glutamate 1-semialdehyde + NADP+ + tRNAGlu
-
-
-
?