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Literature summary extracted from

  • Harris, D.G.; Marx, D.P.; Anderson, J.M.; McCune, R.W.; Zimmerman, S.S.
    Kinetic and molecular modeling of nucleoside and nucleotide inhibition of malate dehydrogenase (2002), Nucleosides Nucleotides Nucleic Acids, 21, 813-823.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.37 ADP competitive Sus scrofa
1.1.1.37 AMP competitive Sus scrofa
1.1.1.37 ATP competitive Sus scrofa
1.1.1.37 cAMP competitive Sus scrofa

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.1.1.37 mitochondrion
-
 Sus scrofa 5739
-

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.37 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.37 heart
-
 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.37 oxaloacetate + NADH
-
 Sus scrofa L-malate + NAD+
-
 r

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.37 NAD+
-
 Sus scrofa
1.1.1.37 NADH
-
 Sus scrofa

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.1.1.37 0.56
-
 cAMP pH 7.4 Sus scrofa
1.1.1.37 0.95
-
 AMP pH 7.4 Sus scrofa
1.1.1.37 1.34
-
 ADP pH 7.4 Sus scrofa
1.1.1.37 1.36
-
 ATP pH 7.4 Sus scrofa