Literature summary extracted from

Romeo, Y.; Obis, D.; Bouvier, J.; Guillot, A.; Four�ans, A.; Bouvier, I.; Gutierrez, C.; Mistou, MY.
Osmoregulation in Lactococcus lactis: BusR, a transcriptional repressor of the glycine betaine uptake system BusA (2003), Mol. Microbiol., 47, 1135-1147.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
7.6.2.9	expression in Escherichia coli	Lactococcus lactis

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
7.6.2.9	BusR	acts as a repressor of busA transcription	Lactococcus lactis
7.6.2.9	NaCl	0.5 M, inhibits	Lactococcus lactis

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
7.6.2.9	membrane	-	Lactococcus lactis	16020	-

Organism

EC Number	Organism	UniProt	Comment	Textmining
7.6.2.9	Lactococcus lactis	-	subspecies cremonis, strain MG1363	-

Reaction

EC Number	Reaction	Comment	Organism	Reaction ID
7.6.2.9	ATP + H2O + quaternary amine-[quaternary amine-binding protein][side 1] = ADP + phosphate + quaternary amine[side 2] + [quaternary amine-binding protein][side 1]	busA locus encodes the glycine betaine uptake system, which expression is reduced by overexpression of busR gene encoding a DNA binding protein	Lactococcus lactis	a

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
7.6.2.9	ATP + H2O + betaine/out	-	Lactococcus lactis	ADP + phosphate + betaine/in	-	?

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Release 2023.1 (January 2023)