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Literature summary extracted from

  • Holm, D.A.; Dagnaes-Hansen, F.; Simonsen, H.; Gregersen, N.; Bolund, L.; Jensen, T.G.; Corydon, T.J.
    Expression of short-chain acyl-CoA dehydrogenase (SCAD) proteins in the liver of SCAD deficient mice after hydrodynamic gene transfer (2003), Mol. Genet. Metab., 78, 250-258.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.3.8.1 expression in mouse liver Homo sapiens

Protein Variants

EC Number Protein Variants Comment Organism
1.3.8.1 G185S 58% of wild-type activity at 41°C after expression in COS-7 cells, mutation may confer susceptibility to accumulation of ethylmalonic acid in affected individuals Homo sapiens
1.3.8.1 R147W 45% and 13% of wild-type activity at 37°Cand 41°C, respectively, after expression in COS-7 cells, mutation may confer susceptibility to accumulation of ethylmalonic acid in affected individuals Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.3.8.1 mitochondrion
-
 Homo sapiens 5739
-

Organism

EC Number Organism UniProt Comment Textmining
1.3.8.1 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.8.1 butanoyl-CoA + acceptor
-
 Homo sapiens 2-butenoyl-CoA + reduced acceptor
-
 r

Synonyms

EC Number Synonyms Comment Organism
1.3.8.1 SCAD
-
 Homo sapiens