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Literature summary extracted from

  • Murmu, J.; Chinthapalli, B.; Raghavendra, A.S.
    Light activation of NADP malic enzyme in leaves of maize: marginal increase in activity, but marked change in regulatory properties of enzyme (2003), J. Plant Physiol., 160, 51-56.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.1.1.40 citrate activation is increased by light exposure Zea mays
1.1.1.40 additional information activation by light with 30% increased Vmax, activation by light is reduced by addition of dithiols Zea mays
1.1.1.40 succinate activation is increased by light exposure Zea mays

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.40 additional information feedback inhibition is reduced by illumination Zea mays
1.1.1.40 oxalate inhibition is decreased by light exposure Zea mays
1.1.1.40 pyruvate inhibition is decreased by light exposure Zea mays

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.40 0.26
-
 L-malate pH 8.0, 30°C, light Zea mays
1.1.1.40 0.28
-
 L-malate pH 8.0, 30°C, dark Zea mays

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.1.1.40 Mg2+
-
 Zea mays

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.40 (S)-malate + NADP+ Zea mays
-
 pyruvate + CO2 + NADPH
-
 ?
1.1.1.40 additional information Zea mays enzyme is regulated by light and dithiols, such as dithioerythritol ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.40 Zea mays
-
 cv. VMH 404
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.40 leaf
-
 Zea mays
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.40 (S)-malate + NADP+
-
 Zea mays pyruvate + CO2 + NADPH
-
 ?
1.1.1.40 additional information enzyme is regulated by light and dithiols, such as dithioerythritol Zea mays ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.1.1.40 NADP malic enzyme
-
 Zea mays
1.1.1.40 NADP-ME
-
 Zea mays

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.1.1.40 30
-
 assay at Zea mays

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.1.1.40 8
-
 assay at Zea mays

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.40 NADP+
-
 Zea mays

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.1.1.40 0.18
-
 oxalate pH 8.0, 30°C, dark Zea mays
1.1.1.40 0.3
-
 oxalate pH 8.0, 30°C, light Zea mays
1.1.1.40 1.3
-
 pyruvate pH 8.0, 30°C, dark Zea mays
1.1.1.40 2.6
-
 pyruvate pH 8.0, 30°C, light Zea mays