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Literature summary extracted from
- Localization of a mitochondrial type of NADP-dependent isocitrate dehydrogenase in kidney and heart of rat: an immunocytochemical and biochemical study (2003), J. Histochem. Cytochem., 51, 215-226.
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 1.1.1.42 | cytosol | isozyme ICD2 | Rattus norvegicus | 5829 | - |
| 1.1.1.42 | mitochondrion | isozyme ICD1, mainly | Rattus norvegicus | 5739 | - |
| 1.1.1.42 | additional information | immunohistochemical determination of the subcellular distribution of isozyme ICD1 in different tissues, overview | Rattus norvegicus | - |
- |
| 1.1.1.42 | nucleus | isozyme ICD1, minor appearance | Rattus norvegicus | 5634 | - |
| 1.1.1.42 | peroxisome | isoyzme ICD2 | Rattus norvegicus | 5777 | - |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.42 | 45000 | - |
x * 45000, isozyme ICD1, SDS-PAGE | Rattus norvegicus |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.1.1.42 | Rattus norvegicus | - |
male Wistar rats, 2 isozymes, ICD1 and ICD2 | - |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 1.1.1.42 | partially, isozyme ICD1 | Rattus norvegicus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.1.1.42 | brown adipose tissue | - |
Rattus norvegicus | - |
| 1.1.1.42 | heart | - |
Rattus norvegicus | - |
| 1.1.1.42 | kidney | - |
Rattus norvegicus | - |
| 1.1.1.42 | liver | low level | Rattus norvegicus | - |
| 1.1.1.42 | additional information | isozyme tissue distribution of isozyme ICD1, overview | Rattus norvegicus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.1.1.42 | isocitrate + NADP+ | - |
Rattus norvegicus | 2-oxoglutarate + CO2 + NADPH + H+ | - |
? |  |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 1.1.1.42 | ? | x * 45000, isozyme ICD1, SDS-PAGE | Rattus norvegicus |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.1.1.42 | ICD | - |
Rattus norvegicus |
| 1.1.1.42 | NADP-dependent isocitrate dehydrogenase | - |
Rattus norvegicus |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.1.1.42 | NADP+ | - |
Rattus norvegicus | |
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