EC Number | Cloned (Comment) | Organism |
---|---|---|
1.11.1.24 | TgTrx-Px1 and TgTrx-Px2, expression in Escherichia coli | Toxoplasma gondii |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.11.1.24 | tert-butyl hydroperoxide | substrate inhibition | Toxoplasma gondii |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.11.1.24 | 0.00004 | - |
tert-butyl hydroperoxide | - |
Toxoplasma gondii | |
1.11.1.24 | 0.00038 | - |
H2O2 | - |
Toxoplasma gondii | |
1.11.1.24 | 0.0042 | - |
thioredoxin | - |
Toxoplasma gondii |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
1.11.1.24 | cytosol | - |
Toxoplasma gondii | 5829 | - |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
1.11.1.24 | 24600 | - |
10 * 24600, TgTrx-Px1, SDS-PAGE | Toxoplasma gondii |
1.11.1.24 | 25000 | - |
TgTrx-Px2 monomer, gel filtration | Toxoplasma gondii |
1.11.1.24 | 26500 | - |
1 * 26500, TgTrx-Px2, SDS-PAGE | Toxoplasma gondii |
1.11.1.24 | 52000 | - |
TgTrx-Px2 dimer, gel filtration | Toxoplasma gondii |
1.11.1.24 | 150000 | - |
TgTrx-Px2 hexamer, gel filtration | Toxoplasma gondii |
1.11.1.24 | 250000 | - |
TgTrx-Px1 decamer, gel filtration | Toxoplasma gondii |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.11.1.24 | additional information | Toxoplasma gondii | peroxidases belonging to the class of 1-Cys and 2-Cys peroxiredoxins play crucial roles in maintaining redox balance. TgTrx-Px1 is an extremely potent antioxidant | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.11.1.24 | Toxoplasma gondii | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.11.1.24 | - |
Toxoplasma gondii |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.11.1.24 | tachyzoite | - |
Toxoplasma gondii | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.11.1.24 | H2O2 + reduced thioredoxin | ping-pong mechanism | Toxoplasma gondii | H2O + oxidized thioredoxin | - |
? | |
1.11.1.24 | additional information | peroxidases belonging to the class of 1-Cys and 2-Cys peroxiredoxins play crucial roles in maintaining redox balance. TgTrx-Px1 is an extremely potent antioxidant | Toxoplasma gondii | ? | - |
? | |
1.11.1.24 | tert-butyl hydroperoxide + reduced thioredoxin | - |
Toxoplasma gondii | tert-butanol + oxidized thioredoxin + H2O | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
1.11.1.24 | decamer | 10 * 24600, TgTrx-Px1, SDS-PAGE | Toxoplasma gondii |
1.11.1.24 | dimer | 1 * 26500, TgTrx-Px2, SDS-PAGE | Toxoplasma gondii |
1.11.1.24 | hexamer | 1 * 26500, TgTrx-Px2, SDS-PAGE | Toxoplasma gondii |
1.11.1.24 | monomer | 1 * 26500, TgTrx-Px2, SDS-PAGE | Toxoplasma gondii |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.11.1.24 | 1-Cys peroxiredoxin | - |
Toxoplasma gondii |
1.11.1.24 | 2-Cys peroxiredoxin | - |
Toxoplasma gondii |
1.11.1.24 | TgTrx-Px1 | - |
Toxoplasma gondii |
1.11.1.24 | TgTrx-Px2 | - |
Toxoplasma gondii |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.11.1.24 | 0.83 | - |
H2O2 | - |
Toxoplasma gondii | |
1.11.1.24 | 2.79 | - |
tert-butyl hydroperoxide | - |
Toxoplasma gondii |