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Literature summary extracted from

  • Rush, J.S.; Cho, S.K.; Jiang, S.; Hofmann, S.L.; Waechter, C.J.
    Identification and characterization of a cDNA encoding a dolichyl pyrophosphate phosphatase located in the endoplasmic reticulum of mammalian cells (2002), J. Biol. Chem., 277, 45226-45234.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.6.1.43 overexpression in Saccharomyces cerevisiae, COS cells and Sf-9 insect cells Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.6.1.43 endoplasmic reticulum
-
 Mus musculus 5783
-

Organism

EC Number Organism UniProt Comment Textmining
3.6.1.43 Mus musculus Q9JMF7 DLPP1 gene
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.6.1.43 brain
-
 Mus musculus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.6.1.43 0.005
-
 pH 7, 30°C, Dol-P-P phosphatase activity using microsomal fractions from Sf-9 cells expressing the enzyme Mus musculus
3.6.1.43 0.016
-
 pH 7, 30°C, Dol-P-P phosphatase activity using microsomal fractions from COS cells expressing the enzyme Mus musculus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.6.1.43 dolichyl diphosphate + H2O
-
 Mus musculus dolichyl phosphate + phosphate
-
 ?
3.6.1.43 additional information enzyme can not hydrolyse dolichyl monophospate Mus musculus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.6.1.43 Dol-P-P phosphatase
-
 Mus musculus
3.6.1.43 dolichyl pyrophosphate phosphatase
-
 Mus musculus