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Literature summary extracted from

  • Zamboni, N.; Fischer, E.; Laudert, D.; Aymerich, S.; Hohmann, H.P.; Sauer, U.
    The Bacillus subtilis yqjI gene encodes the NADP+-dependent 6-P-gluconate dehydrogenase in the pentose phosphate pathway (2004), J. Bacteriol., 186, 4528-4534.
    View publication on PubMedView publication on EuropePMC

Protein Variants

EC Number Protein Variants Comment Organism
1.1.1.44 additional information construction of a knockout mutant Bacillus subtilis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.44 6-phosphono-D-gluconate + NADP+ Bacillus subtilis part of oxidative pentosephosphate pathway, predominant enzyme in glucose and cluconate catabolism, pathway regulation, overview D-ribulose 5-phosphate + CO2 + NADPH
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.44 Bacillus subtilis P80859 gene yqjI, enzyme YpjI
-
1.1.1.343 Bacillus subtilis
-
-
-
1.1.1.343 Bacillus subtilis P12013
-
-
1.1.1.343 Bacillus subtilis 168
-
-
-
1.1.1.343 Bacillus subtilis 168 P12013
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.44 6-phosphono-D-gluconate + NADP+
-
 Bacillus subtilis D-ribulose 5-phosphate + CO2 + NADPH
-
 ?
1.1.1.44 6-phosphono-D-gluconate + NADP+ part of oxidative pentosephosphate pathway, predominant enzyme in glucose and cluconate catabolism, pathway regulation, overview Bacillus subtilis D-ribulose 5-phosphate + CO2 + NADPH
-
 ?
1.1.1.343 6-phospho-D-gluconate + NAD+
-
 Bacillus subtilis D-ribulose 5-phosphate + CO2 + NADH + H+
-
 ?
1.1.1.343 6-phospho-D-gluconate + NAD+
-
 Bacillus subtilis 168 D-ribulose 5-phosphate + CO2 + NADH + H+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.1.1.44 6-P-gluconate dehydrogenase
-
 Bacillus subtilis
1.1.1.44 YpjI
-
 Bacillus subtilis
1.1.1.343 gntZ
-
 Bacillus subtilis
1.1.1.343 NAD+-dependent 6-P gluconate dehydrogenase
-
 Bacillus subtilis
1.1.1.343 NAD+-dependent 6-P-gluconate dehydrogenase
-
 Bacillus subtilis

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.44 NADP+ dependent on Bacillus subtilis
1.1.1.343 NAD+
-
 Bacillus subtilis

General Information

EC Number General Information Comment Organism
1.1.1.343 malfunction gntZ mutants exhibit no detectable phenotype on glucose Bacillus subtilis
1.1.1.343 malfunction gntZ mutants grow normally on glucose Bacillus subtilis
1.1.1.343 physiological function GntZ does not contribute to pentose phosphate pathway fluxes during growth on glucose Bacillus subtilis