Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Woodson, J.D.; Zayas, C.L.; Escalante-Semerena, J.C.
    A new pathway for salvaging the coenzyme B12 precursor cobinamide in archaea requires cobinamide-phosphate synthase (CbiB) enzyme activity (2003), J. Bacteriol., 185, 7193-7201.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
6.3.1.10 cbiB gene, complementation studies Halobacterium sp.
6.3.5.10 cbiP gene Salmonella enterica
6.3.5.10 cbiP gene Halobacterium sp.

Protein Variants

EC Number Protein Variants Comment Organism
6.3.1.10 additional information the cbiB in-frame deletion mutant strain JE6791 does not salvage cobinamide Halobacterium sp.
6.3.5.10 additional information cbiP mutants, nutritional studies Salmonella enterica
6.3.5.10 additional information mutant strain JE6738 with in-frame deletion of cbiP, deficient in cobinamide biosynthesis, auxotrophic for adenosylcorbyric acid Halobacterium sp.

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.3.1.10 additional information Halobacterium sp. CbiB is involved in a salvaging pathway for cobinamide ?
-
 ?
6.3.1.10 additional information Halobacterium sp. NRC-1 CbiB is involved in a salvaging pathway for cobinamide ?
-
 ?
6.3.5.10 ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O Halobacterium sp. cobinamide biosynthesis ADP + phosphate + adenosylcobyric acid + L-glutamate
-
 ?
6.3.5.10 ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O Salmonella enterica involved in the de novo cobinamide biosynthesis pathway ADP + phosphate + adenosylcobyric acid + L-glutamate
-
 ?
6.3.5.10 ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O Halobacterium sp. NRC-1 cobinamide biosynthesis ADP + phosphate + adenosylcobyric acid + L-glutamate
-
 ?
6.3.5.10 ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O Salmonella enterica TR6583 involved in the de novo cobinamide biosynthesis pathway ADP + phosphate + adenosylcobyric acid + L-glutamate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.3.1.10 Halobacterium sp.
-
-
-
6.3.1.10 Halobacterium sp. NRC-1
-
-
-
6.3.5.10 Halobacterium sp.
-
 strains NRC-1 and MPK414
-
6.3.5.10 Salmonella enterica
-
-
-
6.3.5.10 Salmonella enterica TR6583
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
6.3.1.10 ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate = ADP + phosphate + adenosylcobinamide phosphate this enzyme forms part of the anaerobic cobalamin biosynthesis pathway, one of the substrates for this reaction, (R)-1-aminopropan-2-yl phosphate, is produced by CobD, EC 4.1.1.81, threonine phosphate decarboxylase Halobacterium sp.
a

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.3.1.10 ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate
-
 Halobacterium sp. ADP + phosphate + adenosylcobinamide phosphate
-
 ?
6.3.1.10 ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate
-
 Halobacterium sp. NRC-1 ADP + phosphate + adenosylcobinamide phosphate
-
 ?
6.3.1.10 additional information CbiB is involved in a salvaging pathway for cobinamide Halobacterium sp. ?
-
 ?
6.3.1.10 additional information CbiB is involved in a salvaging pathway for cobinamide Halobacterium sp. NRC-1 ?
-
 ?
6.3.5.10 ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O
-
 Salmonella enterica ADP + phosphate + adenosylcobyric acid + L-glutamate
-
 ?
6.3.5.10 ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O
-
 Halobacterium sp. ADP + phosphate + adenosylcobyric acid + L-glutamate
-
 ?
6.3.5.10 ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O cobinamide biosynthesis Halobacterium sp. ADP + phosphate + adenosylcobyric acid + L-glutamate
-
 ?
6.3.5.10 ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O involved in the de novo cobinamide biosynthesis pathway Salmonella enterica ADP + phosphate + adenosylcobyric acid + L-glutamate
-
 ?
6.3.5.10 ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O
-
 Halobacterium sp. NRC-1 ADP + phosphate + adenosylcobyric acid + L-glutamate
-
 ?
6.3.5.10 ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O cobinamide biosynthesis Halobacterium sp. NRC-1 ADP + phosphate + adenosylcobyric acid + L-glutamate
-
 ?
6.3.5.10 ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O
-
 Salmonella enterica TR6583 ADP + phosphate + adenosylcobyric acid + L-glutamate
-
 ?
6.3.5.10 ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O involved in the de novo cobinamide biosynthesis pathway Salmonella enterica TR6583 ADP + phosphate + adenosylcobyric acid + L-glutamate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
6.3.1.10 AdoCbi-P synthase
-
 Halobacterium sp.
6.3.1.10 CbiB
-
 Halobacterium sp.
6.3.5.10 CbiP
-
 Salmonella enterica
6.3.5.10 CbiP
-
 Halobacterium sp.