Literature summary extracted from

Streck, E.L.; Zugno, A.I.; Tagliari, B.; Sarkis, J.J.; Wajner, M.; Wannmacher, C.M.; Wyse, A.T.
On the mechanism of the inhibition of Na(+), K(+)-ATPase activity caused by homocysteine (2002), Int. J. Dev. Neurosci., 20, 77-81.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
7.2.2.13	L-homocysteine	inhibitory effect is reversed by alanine	Rattus norvegicus
7.2.2.13	L-phenylalanine	-	Rattus norvegicus

KM Value [mM]

EC Number	KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
7.2.2.13	0.55	-	ATP	pH 7.4	Rattus norvegicus

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
7.2.2.13	membrane	-	Rattus norvegicus	16020	-

Organism

EC Number	Organism	UniProt	Comment	Textmining
7.2.2.13	Rattus norvegicus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
7.2.2.13	hippocampus	-	Rattus norvegicus	-

Specific Activity [micromol/min/mg]

EC Number	Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
7.2.2.13	0.002	-	-	Rattus norvegicus

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
7.2.2.13	ATP + H2O	-	Rattus norvegicus	ADP + phosphate	-	?

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)