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Literature summary extracted from

  • Kusmierczyk, A.R.; Martin, J.
    Nested cooperativity and salt dependence of the ATPase activity of the archaeal chaperonin Mm-cpn (2003), FEBS Lett., 547, 201-204.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
5.6.1.7 Na+ approx. 40% inhibition at 20 mM, 93% inhibition at 100 mM Methanococcus maripaludis

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
5.6.1.7 additional information
-
 additional information positive intraring cooperativity of ATP is suggested Methanococcus maripaludis

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
5.6.1.7 K+ required for activity, no activity below 10 mM, maximal activity at 600 mM Methanococcus maripaludis
5.6.1.7 Mg2+ required for activity, similar activation between 1 and 50 mM Methanococcus maripaludis
5.6.1.7 NH4+ 200 mM, approx. 40% of activity with 200 mM KCl Methanococcus maripaludis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.6.1.7 ATP + H2O + a folded polypeptide Methanococcus maripaludis
-
 ADP + phosphate + an unfolded polypeptide
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
5.6.1.7 Methanococcus maripaludis
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
5.6.1.7
-
 Methanococcus maripaludis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.6.1.7 ATP + H2O + a folded polypeptide
-
 Methanococcus maripaludis ADP + phosphate + an unfolded polypeptide
-
 ?
5.6.1.7 ATP + H2O + a folded polypeptide Mm-cpn also hydrolyzes with slightly weaker activity CTP, UTP and GTP Methanococcus maripaludis ADP + phosphate + an unfolded polypeptide
-
 ?

Synonyms

EC Number Synonyms Comment Organism
5.6.1.7 Mm-cpn
-
 Methanococcus maripaludis

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
5.6.1.7 8
-
-
 Methanococcus maripaludis

pH Range

EC Number pH Minimum pH Maximum Comment Organism
5.6.1.7 6 9 almost no activity at pH 6.0, approx. 90% of maximal activity at pH 9.0 Methanococcus maripaludis