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Literature summary extracted from

  • Ucar, G.
    Substrate specificities of monoamine oxidase isoforms (2002), FABAD J. Pharm. Sci., 27, 149-156.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.4.3.4 Clorgyline
-
 Rattus norvegicus
1.4.3.4 Pargyline
-
 Homo sapiens
1.4.3.4 Pargyline
-
 Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.4.3.4 0.02
-
 tyramine 37°C Rattus norvegicus
1.4.3.4 0.06
-
 tyramine 37°C Rattus norvegicus
1.4.3.4 0.19
-
 benzylamine
-
 Homo sapiens
1.4.3.4 0.44
-
 serotonin
-
 Rattus norvegicus
1.4.3.4 0.58
-
 benzylamine 37°C Rattus norvegicus
1.4.3.4 1.42
-
 benzylamine 37°C Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.4.3.4 mitochondrion
-
 Rattus norvegicus 5739
-

Organism

EC Number Organism UniProt Comment Textmining
1.4.3.4 Homo sapiens
-
-
-
1.4.3.4 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.4.3.4 blood platelet
-
 Homo sapiens
-
1.4.3.4 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.4.3.4 benzylamine + H2O + O2
-
 Homo sapiens benzaldehyde + NH3 + H2O2
-
 ?
1.4.3.4 benzylamine + H2O + O2
-
 Rattus norvegicus benzaldehyde + NH3 + H2O2
-
 ?
1.4.3.4 additional information no significant activity with serotonin Rattus norvegicus ?
-
 ?
1.4.3.4 serotonin + H2O + O2
-
 Rattus norvegicus (5-hydroxy-1H-indol-3-yl)acetaldehyde + NH3 + H2O2
-
 ?
1.4.3.4 tyramine + H2O + O2
-
 Rattus norvegicus (4-hydroxyphenyl)acetaldehyde + NH3 + H2O2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.4.3.4 MAO-A
-
 Rattus norvegicus
1.4.3.4 MAO-B
-
 Homo sapiens
1.4.3.4 MAO-B
-
 Rattus norvegicus