EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.6.1.5 | 1-hydroxy-naphthalene-3,6-disulfonic acid | - |
Sus scrofa | |
3.6.1.5 | Ba2+ | - |
Sus scrofa | |
3.6.1.5 | Cu2+ | - |
Sus scrofa | |
3.6.1.5 | EDTA | about 40% inhibition at 5 mM | Sus scrofa | |
3.6.1.5 | Sodium azide | - |
Sus scrofa | |
3.6.1.5 | suramin | - |
Sus scrofa |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.6.1.5 | 0.095 | - |
ADP | pH 7.6, 37°C | Sus scrofa | |
3.6.1.5 | 0.097 | - |
ATP | pH 7.6, 37°C | Sus scrofa |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
3.6.1.5 | Ca2+ | - |
Sus scrofa | |
3.6.1.5 | Mg2+ | most effective as activating cation, but not absolutely required | Sus scrofa | |
3.6.1.5 | Mn2+ | activation | Sus scrofa | |
3.6.1.5 | additional information | no effect: Na+ at 100 mM or K+ at 4 mM | Sus scrofa | |
3.6.1.5 | Zn2+ | - |
Sus scrofa |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
3.6.1.5 | 72000 | - |
x * 72000, SDS-PAGE | Sus scrofa |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.6.1.5 | additional information | Sus scrofa | enzyme terminates P2 receptor-mediated signal transmission | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.6.1.5 | Sus scrofa | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.6.1.5 | - |
Sus scrofa |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.6.1.5 | neuronal cell | synaptosome from brain cortex | Sus scrofa | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
3.6.1.5 | 1.3 | - |
pH 7.6, 37°C, presence of 1.5 mM Cu2+ | Sus scrofa |
3.6.1.5 | 4.1 | - |
pH 7.6, 37°C, presence of 1.5 mM Ba2+ | Sus scrofa |
3.6.1.5 | 10.8 | - |
pH 7.6, 37°C, presence of 5 mM EDTA | Sus scrofa |
3.6.1.5 | 19.4 | - |
pH 7.6, 37°C, presence of 1.5 mM Zn2+ | Sus scrofa |
3.6.1.5 | 25.6 | - |
pH 7.6, 37°C | Sus scrofa |
3.6.1.5 | 69.4 | - |
pH 7.6, 37°C, presence of 1.5 mM Ca2+ | Sus scrofa |
3.6.1.5 | 84.2 | - |
pH 7.6, 37°C, presence of 1.5 mM Mn2+ | Sus scrofa |
3.6.1.5 | 94.7 | - |
pH 7.6, 37°C, presence of 1.5 mM Mg2+ | Sus scrofa |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.6.1.5 | ADP + H2O | 71% of activity compared to ATP | Sus scrofa | AMP + phosphate | - |
? | |
3.6.1.5 | ATP + 2 H2O | - |
Sus scrofa | AMP + 2 phosphate | - |
? | |
3.6.1.5 | CDP + H2O | 42% of activity compared to ATP | Sus scrofa | CMP + phosphate | - |
? | |
3.6.1.5 | CTP + 2 H2O | 87% of activity compared to ATP | Sus scrofa | CMP + 2 phosphate | - |
? | |
3.6.1.5 | GDP + H2O | 61% of activity compared to ATP | Sus scrofa | GMP + phosphate | - |
? | |
3.6.1.5 | GTP + 2 H2O | 91% of activity compared to ATP | Sus scrofa | GMP + 2 phosphate | - |
? | |
3.6.1.5 | ITP + 2 H2O | 78% of activity compared to ATP | Sus scrofa | IMP + 2 phosphate | - |
? | |
3.6.1.5 | additional information | enzyme terminates P2 receptor-mediated signal transmission | Sus scrofa | ? | - |
? | |
3.6.1.5 | TDP + H2O | 44% of activity compared to ATP | Sus scrofa | TMP + phosphate | - |
? | |
3.6.1.5 | TTP + 2 H2O | 82% of activity compared to ATP | Sus scrofa | TMP + 2 phosphate | - |
? | |
3.6.1.5 | UDP + H2O | 56% of activity compared to ATP | Sus scrofa | UMP + phosphate | - |
? | |
3.6.1.5 | UTP + 2 H2O | 94% of activity compared to ATP | Sus scrofa | UMP + 2 phosphate | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
3.6.1.5 | ? | x * 72000, SDS-PAGE | Sus scrofa |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.6.1.5 | 860 | - |
ATP | pH 7.6, 37°C | Sus scrofa |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
3.6.1.5 | 7.6 | - |
- |
Sus scrofa |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.6.1.5 | 0.07 | - |
1-hydroxy-naphthalene-3,6-disulfonic acid | pH 7.6, 37°C, substrate ADP | Sus scrofa | |
3.6.1.5 | 0.103 | - |
1-hydroxy-naphthalene-3,6-disulfonic acid | pH 7.6, 37°C, substrate ATP | Sus scrofa | |
3.6.1.5 | 1.7 | - |
suramin | pH 7.6, 37°C, substrate ADP | Sus scrofa | |
3.6.1.5 | 1.8 | - |
suramin | pH 7.6, 37°C, substrate ATP | Sus scrofa | |
3.6.1.5 | 5 | - |
Sodium azide | pH 7.6, 37°C, substrate ADP | Sus scrofa | |
3.6.1.5 | 12 | - |
Sodium azide | pH 7.6, 37°C, substrate ATP | Sus scrofa |
EC Number | Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|---|
3.6.1.5 | Sus scrofa | isoelectric focusing | - |
4.9 |