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Literature summary extracted from

  • Tolstykh, T.; Lee, J.; Vafai, S.; Stock, J.B.
    Carboxyl methylation regulates phosphoprotein phosphatase 2A by controlling the association of regulatory B subunits (2000), EMBO J., 19, 5682-5691.
    View publication on PubMedView publication on EuropePMC

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.3.16 cytoplasm
-
 Bos taurus 5737
-

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.233 Bos taurus
-
-
-
3.1.3.16 Bos taurus
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.1.3.16 side-chain modification methylation of the C-terminus of the catalytic subunit controls the formation of heterotrimeric holoenzymes by increasing the binding of regulatory B subunits Bos taurus

Purification (Commentary)

EC Number Purification (Comment) Organism
2.1.1.233
-
 Bos taurus
3.1.3.16
-
 Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.1.1.233 brain
-
 Bos taurus
-
3.1.3.16 brain
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.233 S-adenosyl-L-methionine + [phosphatase 2A protein]-leucine
-
 Bos taurus S-adenosyl-L-homocysteine + [phosphatase 2A protein]-leucine methyl ester
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.1.1.233 PP2A methyltransferase
-
 Bos taurus
2.1.1.233 PPMT
-
 Bos taurus

General Information

EC Number General Information Comment Organism
2.1.1.233 physiological function methylation by PP2A methyltransferase regulates PP2A phosphatase activity by promoting holoenzyme assembly Bos taurus