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Literature summary extracted from

  • Sopelsa, A.M.; Severini, M.H.; da Silva, C.M.; Tobo, P.R.; Giugliani, R.; Coelho, J.C.
    Characterization of beta-galactosidase in leukocytes and fibroblasts of GM1 gangliosidosis heterozygotes compared to normal subjects (2000), Clin. Biochem., 33, 125-129.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.2.1.23 0.59
-
 4-methylumbelliferyl beta-D-galactoside fibroblast enzyme of GM1 gangliosidosis heterozygotes Homo sapiens
3.2.1.23 0.65
-
 4-methylumbelliferyl beta-D-galactoside leukocyte enzyme of GM1 gangliosidosis heterozygotes Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.23 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.2.1.23 fibroblast of GM1 gangliosidosis heterozygotes compared to normal subjects Homo sapiens
-
3.2.1.23 leukocyte of GM1 gangliosidosis heterozygotes compared to normal subjects Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.23 4-methylumbelliferyl beta-D-galactoside + H2O
-
 Homo sapiens 4-methylumbelliferone + beta-D-galactose
-
 ?

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
3.2.1.23 42
-
 80 min,75% loss of leukocte enzyme from GM1 gangliosidosis heterozygotes,70% loss of fibroblast enzyme from GM1 gangliosidosis heterozygotes Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.2.1.23 4
-
 leukocyte enzyme of GM1 gangliosidosis heterozygotes Homo sapiens
3.2.1.23 4.2
-
 enzyme from leukocytes and fibroblasts of normal individuals, and fibroblast enzyme of GM1 gangliosidosis heterozygotes Homo sapiens