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Literature summary extracted from

  • Fujimoto, K.; Sakurai, M.; Kawase, M.; Katoh, S.
    Effect of antisense oligodeoxynucleotide for sepiapterin reductase on the viability of PC12 cells in the presence of exogenous carbonyl compounds (2003), Chem. Biol. Interact., 143-144, 583-586.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.153 host cells transfected with sense, antisense and inverse antisense oligodeoxynucleotides Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.153 N-acetylserotonin
-
 Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.153 6-pyruvoyl tetrahydropterin + 2 NADPH + 2 H+ Rattus norvegicus final step in the synthesis of tetrahydrobiopterin, role in detoxification of exogenous carbonyl compounds suggested tetrahydrobiopterin + NADP+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.153 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.153 PC-12 cell cell culture model for catecholaminergic neurons Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.153 1-phenyl-1,2-propanedione + NADPH
-
 Rattus norvegicus ?
-
 ?
1.1.1.153 6-pyruvoyl tetrahydropterin + 2 NADPH + 2 H+ final step in the synthesis of tetrahydrobiopterin, role in detoxification of exogenous carbonyl compounds suggested Rattus norvegicus tetrahydrobiopterin + NADP+
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.153 NADPH
-
 Rattus norvegicus