EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.5.2.6 | captopril | - |
Bacillus cereus | |
3.5.2.6 | additional information | pH dependence of inhibition, mechanism, the thiol anion of the cysteinyl peptide inhibitors displaces the hydroxide ion from the active site Zn2+, D,D-peptides bind to the enzyme better than other diastereomers due to the stereochemistry of the active site | Bacillus cereus | |
3.5.2.6 | N(2-mercaptoethyl)phenylacetamide | - |
Bacillus cereus | |
3.5.2.6 | N-carbobenzoxy-D-cysteine | - |
Bacillus cereus | |
3.5.2.6 | N-carbobenzoxy-D-cysteinyl-D-penicillamine | chelates Zn2+ | Bacillus cereus | |
3.5.2.6 | N-carbobenzoxy-D-cysteinyl-D-phenylalanine | - |
Bacillus cereus | |
3.5.2.6 | N-carbobenzoxy-D-cysteinyl-L-phenylalanine | - |
Bacillus cereus | |
3.5.2.6 | N-carbobenzoxy-DL-cysteinyl-glycine | - |
Bacillus cereus | |
3.5.2.6 | N-carbobenzoxy-L-cysteine | - |
Bacillus cereus | |
3.5.2.6 | N-carbobenzoxy-L-cysteinyl-D-phenylalanine | - |
Bacillus cereus | |
3.5.2.6 | N-carbobenzoxy-L-cysteinyl-DL-alanine | - |
Bacillus cereus | |
3.5.2.6 | N-carbobenzoxy-L-cysteinyl-DL-phenylalanine | - |
Bacillus cereus | |
3.5.2.6 | N-carbobenzoxy-L-cysteinyl-DL-proline | - |
Bacillus cereus | |
3.5.2.6 | N-carbobenzoxy-L-cysteinyl-DL-serine | - |
Bacillus cereus | |
3.5.2.6 | N-carbobenzoxy-L-cysteinyl-DL-valine | - |
Bacillus cereus | |
3.5.2.6 | N-carbobenzoxy-L-cysteinyl-glycine | - |
Bacillus cereus | |
3.5.2.6 | N-carbobenzoxy-L-cysteinyl-L-leucine | - |
Bacillus cereus | |
3.5.2.6 | N-carbobenzoxy-L-cysteinyl-L-phenylalanine | - |
Bacillus cereus | |
3.5.2.6 | N-carbobenzoxy-L-cysteinyl-L-serine | - |
Bacillus cereus | |
3.5.2.6 | N-phenylacetyl-DL-penicillamine | - |
Bacillus cereus | |
3.5.2.6 | N-phenylacetyl-L-cysteine | - |
Bacillus cereus | |
3.5.2.6 | N-phenylacetylglycine | - |
Bacillus cereus |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
3.5.2.6 | Zn2+ | dependent on, metalloenzyme, located at the active site | Bacillus cereus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.5.2.6 | Bacillus cereus | - |
- |
- |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.5.2.6 | zinc beta-lactamase | - |
Bacillus cereus |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.5.2.6 | 0.003 | - |
N-carbobenzoxy-D-cysteinyl-D-phenylalanine | pH 7.0, 30°C, 1.0 M NaCl, 0.002 mM Zn2+ | Bacillus cereus | |
3.5.2.6 | 0.009 | - |
N-carbobenzoxy-L-cysteinyl-D-phenylalanine | pH 7.0, 30°C, 1.0 M NaCl, 0.002 mM Zn2+ | Bacillus cereus | |
3.5.2.6 | 0.011 | - |
N-carbobenzoxy-D-cysteinyl-L-phenylalanine | pH 7.0, 30°C, 1.0 M NaCl, 0.002 mM Zn2+ | Bacillus cereus | |
3.5.2.6 | 0.017 | - |
N-carbobenzoxy-L-cysteinyl-DL-phenylalanine | pH 7.0, 30°C, 1.0 M NaCl, 0.002 mM Zn2+ | Bacillus cereus | |
3.5.2.6 | 0.02 | - |
N-carbobenzoxy-D-cysteine | pH 7.0, 30°C, 1.0 M NaCl, 0.002 mM Zn2+ | Bacillus cereus | |
3.5.2.6 | 0.027 | - |
N-carbobenzoxy-L-cysteinyl-L-phenylalanine | pH 7.0, 30°C, 1.0 M NaCl, 0.002 mM Zn2+ | Bacillus cereus | |
3.5.2.6 | 0.042 | - |
captopril | pH 7.0, 30°C, 1.0 M NaCl, 0.002 mM Zn2+ | Bacillus cereus | |
3.5.2.6 | 0.042 | - |
N-carbobenzoxy-L-cysteinyl-glycine | pH 7.0, 30°C, 1.0 M NaCl, 0.002 mM Zn2+ | Bacillus cereus | |
3.5.2.6 | 0.046 | - |
N-carbobenzoxy-DL-cysteinyl-glycine | pH 7.0, 30°C, 1.0 M NaCl, 0.002 mM Zn2+ | Bacillus cereus | |
3.5.2.6 | 0.048 | - |
N-carbobenzoxy-L-cysteinyl-DL-valine | pH 7.0, 30°C, 1.0 M NaCl, 0.002 mM Zn2+ | Bacillus cereus | |
3.5.2.6 | 0.056 | - |
N(2-mercaptoethyl)phenylacetamide | pH 7.0, 30°C, 1.0 M NaCl, 0.002 mM Zn2+ | Bacillus cereus | |
3.5.2.6 | 0.062 | - |
N-carbobenzoxy-L-cysteinyl-DL-alanine | pH 7.0, 30°C, 1.0 M NaCl, 0.002 mM Zn2+ | Bacillus cereus | |
3.5.2.6 | 0.073 | - |
N-carbobenzoxy-L-cysteinyl-DL-serine | pH 7.0, 30°C, 1.0 M NaCl, 0.002 mM Zn2+ | Bacillus cereus | |
3.5.2.6 | 0.084 | - |
N-carbobenzoxy-L-cysteinyl-L-serine | pH 7.0, 30°C, 1.0 M NaCl, 0.002 mM Zn2+ | Bacillus cereus | |
3.5.2.6 | 0.095 | - |
N-carbobenzoxy-L-cysteinyl-DL-proline | pH 7.0, 30°C, 1.0 M NaCl, 0.002 mM Zn2+ | Bacillus cereus | |
3.5.2.6 | 0.097 | - |
N-carbobenzoxy-L-cysteine | pH 7.0, 30°C, 1.0 M NaCl, 0.002 mM Zn2+ | Bacillus cereus | |
3.5.2.6 | 0.108 | - |
N-phenylacetyl-L-cysteine | pH 7.0, 30°C, 1.0 M NaCl, 0.002 mM Zn2+ | Bacillus cereus | |
3.5.2.6 | 0.136 | - |
N-carbobenzoxy-L-cysteinyl-L-leucine | pH 7.0, 30°C, 1.0 M NaCl, 0.002 mM Zn2+ | Bacillus cereus | |
3.5.2.6 | 0.515 | - |
N-phenylacetyl-DL-penicillamine | pH 7.0, 30°C, 1.0 M NaCl, 0.002 mM Zn2+ | Bacillus cereus | |
3.5.2.6 | 1 | - |
N-phenylacetylglycine | pH 7.0, 30°C, 1.0 M NaCl, 0.002 mM Zn2+ | Bacillus cereus |