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Literature summary extracted from

  • Scozzafava, A.; Supuran, C.T.
    Protease inhibitors. Part 8. Synthesis of potent Clostridium histolyticum collagenase inhibitors incorporating sulfonylated L-alanine hydroxamate moieties (2000), Bioorg. Med. Chem., 8, 637-645.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.24.3 3-[(2-chlorobenzyl)[(1S)-2-(hydroxyamino)-1-methyl-2-oxoethyl]sulfamoyl]benzoic acid
-
 Hathewaya histolytica
3.4.24.3 3-[[(1S)-1-carboxyethyl](2-chlorobenzyl)sulfamoyl]benzoic acid
-
 Hathewaya histolytica
3.4.24.3 4-[(2-chlorobenzyl)[(1S)-2-(hydroxyamino)-1-methyl-2-oxoethyl]sulfamoyl]benzoic acid
-
 Hathewaya histolytica
3.4.24.3 4-[[(1S)-1-carboxyethyl](2-chlorobenzyl)sulfamoyl]benzoic acid
-
 Hathewaya histolytica
3.4.24.3 N-(2-chlorobenzyl)-N-(dimethylsulfamoyl)-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-(2-chlorobenzyl)-N-(methylsulfonyl)-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-(2-chlorobenzyl)-N-(naphthalen-1-ylcarbamoyl)-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-(2-chlorobenzyl)-N-(naphthalen-1-ylsulfonyl)-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-(2-chlorobenzyl)-N-(naphthalen-2-ylsulfonyl)-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-(2-chlorobenzyl)-N-(phenylsulfonyl)-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-(2-chlorobenzyl)-N-(thiophen-2-ylsulfonyl)-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-(2-chlorobenzyl)-N-[(2,4,6-trimethylphenyl)sulfonyl]-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-(2-chlorobenzyl)-N-[(2,4-difluorophenyl)carbamoyl]-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-(2-chlorobenzyl)-N-[(2,4-dinitrophenyl)sulfanyl]-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-(2-chlorobenzyl)-N-[(2,5-dichlorophenyl)sulfonyl]-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-(2-chlorobenzyl)-N-[(2-nitrophenyl)sulfanyl]-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-(2-chlorobenzyl)-N-[(2-nitrophenyl)sulfonyl]-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-(2-chlorobenzyl)-N-[(3,4-dichlorophenyl)carbamoyl]-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-(2-chlorobenzyl)-N-[(3,5-dichloro-2-hydroxyphenyl)sulfonyl]-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-(2-chlorobenzyl)-N-[(3-chloro-4-nitrophenyl)sulfonyl]-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-(2-chlorobenzyl)-N-[(3-chlorophenyl)carbamoyl]-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-(2-chlorobenzyl)-N-[(3-nitrophenyl)sulfonyl]-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-(2-chlorobenzyl)-N-[(4-bromophenyl)sulfonyl]-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-(2-chlorobenzyl)-N-[(4-chlorophenyl)carbamoyl]-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-(2-chlorobenzyl)-N-[(4-chlorophenyl)sulfonyl]-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-(2-chlorobenzyl)-N-[(4-fluorophenyl)carbamoyl]-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-(2-chlorobenzyl)-N-[(4-fluorophenyl)sulfonyl]-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-(2-chlorobenzyl)-N-[(4-iodophenyl)sulfonyl]-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-(2-chlorobenzyl)-N-[(4-methoxyphenyl)sulfonyl]-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-(2-chlorobenzyl)-N-[(4-methylphenyl)sulfonyl]-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-(2-chlorobenzyl)-N-[(4-nitrophenyl)sulfanyl]-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-(2-chlorobenzyl)-N-[(4-nitrophenyl)sulfonyl]-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-(2-chlorobenzyl)-N-[(heptadecafluorooctyl)sulfonyl]-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-(2-chlorobenzyl)-N-[(nonafluorobutyl)sulfonyl]-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-(2-chlorobenzyl)-N-[(trichloromethyl)sulfonyl]-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-(2-chlorobenzyl)-N-[(trifluoromethyl)sulfonyl]-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-(2-chlorobenzyl)-N-[[(2-methylphenyl)sulfonyl]carbamoyl]-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-(2-chlorobenzyl)-N-[[(4-chlorophenyl)sulfonyl]carbamoyl]-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-(2-chlorobenzyl)-N-[[(4-fluorophenyl)sulfonyl]carbamoyl]-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-(2-chlorobenzyl)-N-[[(4-methylphenyl)sulfonyl]carbamoyl]-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-(2-chlorobenzyl)-N-[[3-(trifluoromethyl)phenyl]sulfonyl]-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-(2-chlorobenzyl)-N-[[5-(dimethylamino)naphthalen-1-yl]sulfonyl]-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-(benzylsulfonyl)-N-(2-chlorobenzyl)-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-([(2-chlorobenzyl)[(1S)-2-(hydroxyamino)-1-methyl-2-oxoethyl]amino]methyl)benzamide
-
 Hathewaya histolytica
3.4.24.3 N-([3-[(tert-butoxycarbonyl)amino]-4-methoxyphenyl]sulfonyl)-N-(2-chlorobenzyl)-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-([3-[(tert-butoxycarbonyl)amino]phenyl]sulfonyl)-N-(2-chlorobenzyl)-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-([4-[(tert-butoxycarbonyl)amino]phenyl]sulfonyl)-N-(2-chlorobenzyl)-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N-[[4-(acetylamino)phenyl]sulfonyl]-N-(2-chlorobenzyl)-L-alanine
-
 Hathewaya histolytica
3.4.24.3 N2(2-chlorobenzyl)-N-hydroxy-N2-[(trifluoromethyl)sulfonyl]-L-alaninamide
-
 Hathewaya histolytica
3.4.24.3 N2-(2-chlorobenzyl)-N-hydroxy-N2-(naphthalen-1-ylcarbamoyl)-L-alaninamide
-
 Hathewaya histolytica
3.4.24.3 N2-(2-chlorobenzyl)-N-hydroxy-N2-(naphthalen-1-ylsulfonyl)-L-alaninamide
-
 Hathewaya histolytica
3.4.24.3 N2-(2-chlorobenzyl)-N-hydroxy-N2-(naphthalen-2-ylsulfonyl)-L-alaninamide
-
 Hathewaya histolytica
3.4.24.3 N2-(2-chlorobenzyl)-N-hydroxy-N2-(phenylsulfonyl)-L-alaninamide
-
 Hathewaya histolytica
3.4.24.3 N2-(2-chlorobenzyl)-N-hydroxy-N2-(quinolin-8-ylsulfonyl)-L-alaninamide
-
 Hathewaya histolytica
3.4.24.3 N2-(2-chlorobenzyl)-N-hydroxy-N2-(thiophen-2-ylsulfonyl)-L-alaninamide
-
 Hathewaya histolytica
3.4.24.3 N2-(2-chlorobenzyl)-N-hydroxy-N2-[(2,4,6-trimethylphenyl)sulfonyl]-L-alaninamide
-
 Hathewaya histolytica
3.4.24.3 N2-(2-chlorobenzyl)-N-hydroxy-N2-[(2,4-dinitrophenyl)sulfanyl]-L-alaninamide
-
 Hathewaya histolytica
3.4.24.3 N2-(2-chlorobenzyl)-N-hydroxy-N2-[(4-methoxyphenyl)sulfonyl]-L-alaninamide
-
 Hathewaya histolytica
3.4.24.3 N2-(2-chlorobenzyl)-N-hydroxy-N2-[(4-nitrophenyl)sulfanyl]-L-alaninamide
-
 Hathewaya histolytica
3.4.24.3 N2-(2-chlorobenzyl)-N-hydroxy-N2-[(nonafluorobutyl)sulfonyl]-L-alaninamide
-
 Hathewaya histolytica
3.4.24.3 N2-(2-chlorobenzyl)-N-hydroxy-N2-[(trichloromethyl)sulfonyl]-L-alaninamide
-
 Hathewaya histolytica
3.4.24.3 N2-(2-chlorobenzyl)-N-hydroxy-N2-[[3-(trifluoromethyl)phenyl]sulfonyl]-L-alaninamide
-
 Hathewaya histolytica
3.4.24.3 N2-(2-chlorobenzyl)-N2-(dimethylsulfamoyl)-N-hydroxy-L-alaninamide
-
 Hathewaya histolytica
3.4.24.3 N2-(2-chlorobenzyl)-N2-[(2,4-difluorophenyl)carbamoyl]-N-hydroxy-L-alaninamide
-
 Hathewaya histolytica
3.4.24.3 N2-(2-chlorobenzyl)-N2-[(2,5-dichlorophenyl)sulfonyl]-N-hydroxy-L-alaninamide
-
 Hathewaya histolytica
3.4.24.3 N2-(2-chlorobenzyl)-N2-[(2-nitrophenyl)sulfonyl]-N-hydroxy-L-alaninamide
-
 Hathewaya histolytica
3.4.24.3 N2-(2-chlorobenzyl)-N2-[(3,4-dichlorophenyl)carbamoyl]-N-hydroxy-L-alaninamide
-
 Hathewaya histolytica
3.4.24.3 N2-(2-chlorobenzyl)-N2-[(3,5-dichloro-2-hydroxyphenyl)sulfonyl]-N-hydroxy-L-alaninamide
-
 Hathewaya histolytica
3.4.24.3 N2-(2-chlorobenzyl)-N2-[(3-chloro-4-nitrophenyl)sulfonyl]-N-hydroxy-L-alaninamide
-
 Hathewaya histolytica
3.4.24.3 N2-(2-chlorobenzyl)-N2-[(3-chlorophenyl)carbamoyl]-N-hydroxy-L-alaninamide
-
 Hathewaya histolytica
3.4.24.3 N2-(2-chlorobenzyl)-N2-[(3-nitrophenyl)sulfonyl]-N-hydroxy-L-alaninamide
-
 Hathewaya histolytica
3.4.24.3 N2-(2-chlorobenzyl)-N2-[(4-bromophenyl)sulfonyl]-N-hydroxy-L-alaninamide
-
 Hathewaya histolytica
3.4.24.3 N2-(2-chlorobenzyl)-N2-[(4-chlorophenyl)carbamoyl]-N-hydroxy-L-alaninamide
-
 Hathewaya histolytica
3.4.24.3 N2-(2-chlorobenzyl)-N2-[(4-chlorophenyl)sulfonyl]-N-hydroxy-L-alaninamide
-
 Hathewaya histolytica
3.4.24.3 N2-(2-chlorobenzyl)-N2-[(4-fluorophenyl)carbamoyl]-N-hydroxy-L-alaninamide
-
 Hathewaya histolytica
3.4.24.3 N2-(2-chlorobenzyl)-N2-[(4-fluorophenyl)sulfonyl]-N-hydroxy-L-alaninamide
-
 Hathewaya histolytica
3.4.24.3 N2-(2-chlorobenzyl)-N2-[(4-iodophenyl)sulfonyl]-N-hydroxy-L-alaninamide
-
 Hathewaya histolytica
3.4.24.3 N2-(2-chlorobenzyl)-N2-[(4-methylphenyl)sulfonyl]-N-hydroxy-L-alaninamide
-
 Hathewaya histolytica
3.4.24.3 N2-(2-chlorobenzyl)-N2-[(4-nitrophenyl)sulfonyl]-N-hydroxy-L-alaninamide
-
 Hathewaya histolytica
3.4.24.3 N2-(2-chlorobenzyl)-N2-[(heptadecafluorooctyl)sulfonyl]-N-hydroxy-L-alaninamide
-
 Hathewaya histolytica
3.4.24.3 N2-(2-chlorobenzyl)-N2-[[(2-methylphenyl)sulfonyl]carbamoyl]-N-hydroxy-L-alaninamide
-
 Hathewaya histolytica
3.4.24.3 N2-(2-chlorobenzyl)-N2-[[(4-chlorophenyl)sulfonyl]carbamoyl]-N-hydroxy-L-alaninamide
-
 Hathewaya histolytica
3.4.24.3 N2-(2-chlorobenzyl)-N2-[[(4-fluorophenyl)sulfonyl]carbamoyl]-N-hydroxy-L-alaninamide
-
 Hathewaya histolytica
3.4.24.3 N2-(2-chlorobenzyl)-N2-[[(4-methylphenyl)sulfonyl]carbamoyl]-N-hydroxy-L-alaninamide
-
 Hathewaya histolytica
3.4.24.3 N2-(2-chlorobenzyl)-N2-[[5-(dimethylamino)naphthalen-1-yl]sulfonyl]-N-hydroxy-L-alaninamide
-
 Hathewaya histolytica
3.4.24.3 N2-(benzylsulfonyl)-N2-(2-chlorobenzyl)-N-hydroxy-L-alaninamide
-
 Hathewaya histolytica
3.4.24.3 N2-chlorobenzyl)-N-hydroxy-N2-(methylsulfonyl)-L-alaninamide
-
 Hathewaya histolytica
3.4.24.3 N2-[[4-(acetylamino)phenyl]sulfonyl]-N2-(2-chlorobenzyl)-N-hydroxy-L-alaninamide
-
 Hathewaya histolytica
3.4.24.3 tert-butyl (3-[(2-chlorobenzyl)[(1S)-2-(hydroxyamino)-1-methyl-2-oxoethyl]sulfamoyl]phenyl)carbamate
-
 Hathewaya histolytica
3.4.24.3 tert-butyl (4-[(2-chlorobenzyl)[(1S)-2-(hydroxyamino)-1-methyl-2-oxoethyl]sulfamoyl]phenyl)carbamate
-
 Hathewaya histolytica
3.4.24.3 tert-butyl (5-[(2-chlorobenzyl)[(1S)-2-(hydroxyamino)-1-methyl-2-oxoethyl]sulfamoyl]-2-methoxyphenyl)carbamate
-
 Hathewaya histolytica

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.24.3 Zinc metallopeptidase Hathewaya histolytica

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.3 Hathewaya histolytica
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.3 Collagen + H2O triple helical collagen Hathewaya histolytica ?
-
 ?
3.4.24.3 furanacryloyl-Leu-Gly-Pro-Ala + H2O
-
 Hathewaya histolytica furanacryloyl-Leu + Gly-Pro-Ala
-
 ?

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
3.4.24.3 0.0000005
-
 N2-(2-chlorobenzyl)-N-hydroxy-N2-(phenylsulfonyl)-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000006
-
 N2-(2-chlorobenzyl)-N-hydroxy-N2-[[3-(trifluoromethyl)phenyl]sulfonyl]-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000006
-
 N-([(2-chlorobenzyl)[(1S)-2-(hydroxyamino)-1-methyl-2-oxoethyl]amino]methyl)benzamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000007
-
 4-[(2-chlorobenzyl)[(1S)-2-(hydroxyamino)-1-methyl-2-oxoethyl]sulfamoyl]benzoic acid pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000007
-
 N2-(2-chlorobenzyl)-N-hydroxy-N2-(quinolin-8-ylsulfonyl)-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000008
-
 N2-(2-chlorobenzyl)-N2-[[(4-fluorophenyl)sulfonyl]carbamoyl]-N-hydroxy-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000008
-
 N2-(2-chlorobenzyl)-N2-[(heptadecafluorooctyl)sulfonyl]-N-hydroxy-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000008
-
 tert-butyl (3-[(2-chlorobenzyl)[(1S)-2-(hydroxyamino)-1-methyl-2-oxoethyl]sulfamoyl]phenyl)carbamate pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000008
-
 tert-butyl (5-[(2-chlorobenzyl)[(1S)-2-(hydroxyamino)-1-methyl-2-oxoethyl]sulfamoyl]-2-methoxyphenyl)carbamate pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000008
-
 3-[(2-chlorobenzyl)[(1S)-2-(hydroxyamino)-1-methyl-2-oxoethyl]sulfamoyl]benzoic acid pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000008
-
 N2-(2-chlorobenzyl)-N-hydroxy-N2-(naphthalen-1-ylsulfonyl)-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000009
-
 N2-(2-chlorobenzyl)-N2-[[(4-fluorophenyl)sulfonyl]carbamoyl]-N-hydroxy-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000009
-
 tert-butyl (4-[(2-chlorobenzyl)[(1S)-2-(hydroxyamino)-1-methyl-2-oxoethyl]sulfamoyl]phenyl)carbamate pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000009
-
 N2-(2-chlorobenzyl)-N2-[(3,5-dichloro-2-hydroxyphenyl)sulfonyl]-N-hydroxy-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000009
-
 N2-(2-chlorobenzyl)-N-hydroxy-N2-(naphthalen-2-ylsulfonyl)-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.00001
-
 N2-(2-chlorobenzyl)-N2-[(3-chloro-4-nitrophenyl)sulfonyl]-N-hydroxy-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.00001
-
 N2-(2-chlorobenzyl)-N2-[[5-(dimethylamino)naphthalen-1-yl]sulfonyl]-N-hydroxy-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.00001
-
 N2-(2-chlorobenzyl)-N2-[[(4-methylphenyl)sulfonyl]carbamoyl]-N-hydroxy-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000011
-
 N2-(2-chlorobenzyl)-N-hydroxy-N2-[(nonafluorobutyl)sulfonyl]-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000011
-
 N2-(2-chlorobenzyl)-N2-[(3-nitrophenyl)sulfonyl]-N-hydroxy-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000011
-
 N2-[[4-(acetylamino)phenyl]sulfonyl]-N2-(2-chlorobenzyl)-N-hydroxy-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000011
-
 N2-(2-chlorobenzyl)-N-hydroxy-N2-(thiophen-2-ylsulfonyl)-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000011
-
 N2-(2-chlorobenzyl)-N2-[[(4-chlorophenyl)sulfonyl]carbamoyl]-N-hydroxy-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000011
-
 N2-(2-chlorobenzyl)-N-hydroxy-N2-(naphthalen-1-ylcarbamoyl)-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000011
-
 N2-(2-chlorobenzyl)-N-hydroxy-N2-[(2,4-dinitrophenyl)sulfanyl]-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000013
-
 N2-(2-chlorobenzyl)-N-hydroxy-N2-[(4-nitrophenyl)sulfanyl]-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000014
-
 N2-(2-chlorobenzyl)-N2-[(2,4-difluorophenyl)carbamoyl]-N-hydroxy-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000015
-
 N2-(2-chlorobenzyl)-N2-[(4-nitrophenyl)sulfonyl]-N-hydroxy-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000015
-
 N2-(2-chlorobenzyl)-N2-[(2,5-dichlorophenyl)sulfonyl]-N-hydroxy-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000015
-
 N2-(2-chlorobenzyl)-N2-[(4-chlorophenyl)carbamoyl]-N-hydroxy-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000015
-
 N2-(2-chlorobenzyl)-N2-[(3,4-dichlorophenyl)carbamoyl]-N-hydroxy-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000016
-
 N2-(2-chlorobenzyl)-N2-[(2-nitrophenyl)sulfonyl]-N-hydroxy-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000017
-
 N2-(2-chlorobenzyl)-N-hydroxy-N2-[(2,4,6-trimethylphenyl)sulfonyl]-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000017
-
 N2-(2-chlorobenzyl)-N2-[(3-chlorophenyl)carbamoyl]-N-hydroxy-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000018
-
 N2-(2-chlorobenzyl)-N2-[(4-fluorophenyl)carbamoyl]-N-hydroxy-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000022
-
 N2-(2-chlorobenzyl)-N-hydroxy-N2-[(4-methoxyphenyl)sulfonyl]-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.00003
-
 N2-(2-chlorobenzyl)-N2-[(4-iodophenyl)sulfonyl]-N-hydroxy-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000033
-
 N2-(2-chlorobenzyl)-N2-[(4-bromophenyl)sulfonyl]-N-hydroxy-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000035
-
 N2-(2-chlorobenzyl)-N2-[(4-chlorophenyl)sulfonyl]-N-hydroxy-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000036
-
 N2-(2-chlorobenzyl)-N2-[(4-fluorophenyl)sulfonyl]-N-hydroxy-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000045
-
 N2-(2-chlorobenzyl)-N2-[(4-methylphenyl)sulfonyl]-N-hydroxy-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000054
-
 N2-(benzylsulfonyl)-N2-(2-chlorobenzyl)-N-hydroxy-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000058
-
 N2-(2-chlorobenzyl)-N-hydroxy-N2-(phenylsulfonyl)-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000071
-
 N2-(2-chlorobenzyl)-N-hydroxy-N2-[(trichloromethyl)sulfonyl]-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000076
-
 N2(2-chlorobenzyl)-N-hydroxy-N2-[(trifluoromethyl)sulfonyl]-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000077
-
 N2-(2-chlorobenzyl)-N2-(dimethylsulfamoyl)-N-hydroxy-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.000092
-
 N2-chlorobenzyl)-N-hydroxy-N2-(methylsulfonyl)-L-alaninamide pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.0004
-
 N-(2-chlorobenzyl)-N-(phenylsulfonyl)-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.0005
-
 N-(2-chlorobenzyl)-N-[[3-(trifluoromethyl)phenyl]sulfonyl]-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.0015
-
 N-(2-chlorobenzyl)-N-[(heptadecafluorooctyl)sulfonyl]-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.0015
-
 N-(2-chlorobenzyl)-N-(naphthalen-2-ylsulfonyl)-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.0016
-
 N-(2-chlorobenzyl)-N-(naphthalen-1-ylsulfonyl)-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.002
-
 N-(2-chlorobenzyl)-N-(thiophen-2-ylsulfonyl)-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.0021
-
 N-(2-chlorobenzyl)-N-[[5-(dimethylamino)naphthalen-1-yl]sulfonyl]-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.0024
-
 N-(2-chlorobenzyl)-N-(thiophen-2-ylsulfonyl)-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.0024
-
 N-([3-[(tert-butoxycarbonyl)amino]phenyl]sulfonyl)-N-(2-chlorobenzyl)-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.0024
-
 N-(2-chlorobenzyl)-N-[(3,5-dichloro-2-hydroxyphenyl)sulfonyl]-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.0027
-
 N-([4-[(tert-butoxycarbonyl)amino]phenyl]sulfonyl)-N-(2-chlorobenzyl)-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.003
-
 N-(2-chlorobenzyl)-N-[(nonafluorobutyl)sulfonyl]-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.003
-
 N-[[4-(acetylamino)phenyl]sulfonyl]-N-(2-chlorobenzyl)-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.003
-
 N-([3-[(tert-butoxycarbonyl)amino]-4-methoxyphenyl]sulfonyl)-N-(2-chlorobenzyl)-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.0031
-
 N-(2-chlorobenzyl)-N-[(3-chloro-4-nitrophenyl)sulfonyl]-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.0033
-
 N-(2-chlorobenzyl)-N-[(trifluoromethyl)sulfonyl]-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.0034
-
 N-(2-chlorobenzyl)-N-[[(4-chlorophenyl)sulfonyl]carbamoyl]-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.0036
-
 N-(2-chlorobenzyl)-N-[[(4-fluorophenyl)sulfonyl]carbamoyl]-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.0038
-
 4-[[(1S)-1-carboxyethyl](2-chlorobenzyl)sulfamoyl]benzoic acid pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.004
-
 N-(2-chlorobenzyl)-N-[[(2-methylphenyl)sulfonyl]carbamoyl]-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.0041
-
 N-(2-chlorobenzyl)-N-[[(4-methylphenyl)sulfonyl]carbamoyl]-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.0041
-
 N-(2-chlorobenzyl)-N-[(2,5-dichlorophenyl)sulfonyl]-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.0041
-
 3-[[(1S)-1-carboxyethyl](2-chlorobenzyl)sulfamoyl]benzoic acid pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.0049
-
 N-(2-chlorobenzyl)-N-[(2-nitrophenyl)sulfonyl]-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.005
-
 N-(2-chlorobenzyl)-N-[(3-nitrophenyl)sulfonyl]-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.005
-
 N-(2-chlorobenzyl)-N-(naphthalen-1-ylcarbamoyl)-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.0051
-
 N-(2-chlorobenzyl)-N-[(4-nitrophenyl)sulfonyl]-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.0052
-
 N-(2-chlorobenzyl)-N-[(trichloromethyl)sulfonyl]-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.0055
-
 N-(2-chlorobenzyl)-N-[(2,4-difluorophenyl)carbamoyl]-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.0058
-
 N-(2-chlorobenzyl)-N-[(3,4-dichlorophenyl)carbamoyl]-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.006
-
 N-(2-chlorobenzyl)-N-[(4-methoxyphenyl)sulfonyl]-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.0068
-
 N-(2-chlorobenzyl)-N-[(2,4,6-trimethylphenyl)sulfonyl]-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.0068
-
 N-(2-chlorobenzyl)-N-[(4-chlorophenyl)carbamoyl]-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.0074
-
 N-(2-chlorobenzyl)-N-[(4-fluorophenyl)carbamoyl]-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.0076
-
 N-(2-chlorobenzyl)-N-[(3-chlorophenyl)carbamoyl]-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.01
-
 N-(2-chlorobenzyl)-N-[(4-bromophenyl)sulfonyl]-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.01
-
 N-(2-chlorobenzyl)-N-[(4-iodophenyl)sulfonyl]-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.012
-
 N-(2-chlorobenzyl)-N-[(4-fluorophenyl)sulfonyl]-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.013
-
 N-(2-chlorobenzyl)-N-[(4-chlorophenyl)sulfonyl]-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.016
-
 N-(benzylsulfonyl)-N-(2-chlorobenzyl)-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.018
-
 N-(2-chlorobenzyl)-N-[(4-methylphenyl)sulfonyl]-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.021
-
 N-(2-chlorobenzyl)-N-(methylsulfonyl)-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.024
-
 N-(2-chlorobenzyl)-N-(phenylsulfonyl)-L-alanine pH 7.5, 25°C Hathewaya histolytica
3.4.24.3 0.04
-
 N-(2-chlorobenzyl)-N-(dimethylsulfamoyl)-L-alanine pH 7.5, 25°C Hathewaya histolytica