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Literature summary extracted from

  • Husen, B.; Adamski, J.; Bruns, A.; Deluca, D.; Fuhrmann, K.; Moller, G.; Schwabe, I.; Einspanier, A.
    Characterization of 17beta-hydroxysteroid dehydrogenase type 7 in reproductive tissues of the marmoset monkey (2003), Biol. Reprod., 68, 2092-2099.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.62
-
 Callithrix jacchus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.62 estrone + NADPH + H+ Callithrix jacchus final step in the synthesis of active estrogens, important in the maintenance of pregnancy estradiol-17beta + NADP+
-
 ?
1.1.1.62 estrone + NADPH + H+ Callithrix jacchus final step in the synthesis of active estrogens, important in the maintenance of pregnancy estradiol-17beta + NADP+
-
 r

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.62 Callithrix jacchus Q9GME2 marmoset monkey, isoform 1, 17beta-HSD1
-
1.1.1.62 Callithrix jacchus Q9N0M8 marmoset monkey, isoform 7, 17beta-HSD7
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.62 adrenal gland
-
 Callithrix jacchus
-
1.1.1.62 colon
-
 Callithrix jacchus
-
1.1.1.62 corpus luteum detectable throughout the luteal phase of the ovarian cycle and during pregnancy Callithrix jacchus
-
1.1.1.62 jejunum
-
 Callithrix jacchus
-
1.1.1.62 kidney
-
 Callithrix jacchus
-
1.1.1.62 liver high activity Callithrix jacchus
-
1.1.1.62 additional information not detectable in brain, colon, jejunum, pancreas, kidney, liver, adrenal, prostate, testis, uterus, lung, and spleen Callithrix jacchus
-
1.1.1.62 additional information not detectable in brain, lung and spleen Callithrix jacchus
-
1.1.1.62 pancreas
-
 Callithrix jacchus
-
1.1.1.62 placenta
-
 Callithrix jacchus
-
1.1.1.62 prostate gland
-
 Callithrix jacchus
-
1.1.1.62 testis
-
 Callithrix jacchus
-
1.1.1.62 uterus
-
 Callithrix jacchus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.62 estrone + NADPH + H+
-
 Callithrix jacchus estradiol-17beta + NADP+
-
 ?
1.1.1.62 estrone + NADPH + H+ final step in the synthesis of active estrogens, important in the maintenance of pregnancy Callithrix jacchus estradiol-17beta + NADP+
-
 ?
1.1.1.62 estrone + NADPH + H+ final step in the synthesis of active estrogens, important in the maintenance of pregnancy Callithrix jacchus estradiol-17beta + NADP+
-
 r
1.1.1.62 estrone + NADPH + H+ reductive activity is 1.5-3fold higher than oxidative activity Callithrix jacchus estradiol-17beta + NADP+
-
 r

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.62 NADPH
-
 Callithrix jacchus