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Literature summary extracted from

  • Senthilkumaran, B.; Sudhakumari, C.C.; Chang, X.T.; Kobayashi, T.; Oba, Y.; Guan, G.; Yoshiura, Y.; Yoshikuni, M.; Nagahama, Y.
    Ovarian carbonyl reductase-like 20beta-hydroxysteroid dehydrogenase shows distinct surge in messenger RNA expression during natural and gonadotropin-induced meiotic maturation in Nile tilapia (2002), Biol. Reprod., 67, 1080-1086.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.53 expression in Escherichia coli Oreochromis niloticus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.53 additional information Oreochromis niloticus the enzyme plays an important role in the meiotic maturation of tilapia gametes ?
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?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.53 Oreochromis niloticus Q8UVJ2
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-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.53 gill
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Oreochromis niloticus
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1.1.1.53 ovary expression in ovarian follicles is low from day 0 to day 8 after spawning and is not detectable on day 11. Distinct expression is evident at day 14, the day of spawning Oreochromis niloticus
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1.1.1.53 testis expressed continually in matire testes but not in immature testes of 30-day-old fish Oreochromis niloticus
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.53 17alpha-hydroxyprogesterone + NADPH + H+ 4.3% of the activity with p-nitrobenzaldehyde Oreochromis niloticus 17alpha,20beta-dihydroxy-4-pregnene-3-one + NADP+
-
?
1.1.1.53 5alpha-dihydrotestosterone + NADPH + H+ 14.4% of the activity with p-nitrobenzaldehyde Oreochromis niloticus 5alpha-androstan-3alpha,17beta-diol + NADP+
-
?
1.1.1.53 5beta-dihydrotestosterone + NADPH 9.2% of the activity with p-nitrobenzaldehyde Oreochromis niloticus 5beta-androstan-3alpha,17beta-diol + NADP+
-
?
1.1.1.53 menadione + NADPH 75% of the activity with p-nitrobenzaldehyde Oreochromis niloticus ?
-
?
1.1.1.53 additional information the enzyme plays an important role in the meiotic maturation of tilapia gametes Oreochromis niloticus ?
-
?
1.1.1.53 p-nitrobenzaldehyde + NADPH
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Oreochromis niloticus p-nitrobenzyl alcohol + NADP+
-
?
1.1.1.53 progesterone + NADPH 2.5% of the activity with p-nitrobenzaldehyde Oreochromis niloticus 20beta-hydroxy-pregn-4-ene-3-one + NADP+
-
?

Synonyms

EC Number Synonyms Comment Organism
1.1.1.53 20beta-HSD
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Oreochromis niloticus
1.1.1.53 carbonyl reductase-like 20beta-hydroxysteroid dehydrogenase
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Oreochromis niloticus