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Literature summary extracted from
- Large-scale purification, dissociation and functional reassembly of the maltose ATP-binding cassette transporter (MalFGK2) of Salmonella typhimurium (2002), Biochim. Biophys. Acta, 1565, 64-72.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 7.5.2.1 | expression in Escherichia coli | Salmonella enterica subsp. enterica serovar Typhimurium |
Protein Variants
| EC Number | Protein Variants | Comment | Organism |
|---|---|---|---|
| 7.5.2.1 | Q140K | normal intrinsic ATPase activity in soluble state but no hydrolysis of ATP when assembled with MalFG | Salmonella enterica subsp. enterica serovar Typhimurium |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 7.5.2.1 | enzyme IIA Glc | - |
Salmonella enterica subsp. enterica serovar Typhimurium | |
| 7.5.2.1 | vanadate | - |
Salmonella enterica subsp. enterica serovar Typhimurium |  |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 7.5.2.1 | 0.1 | - |
ATP | - |
Salmonella enterica subsp. enterica serovar Typhimurium | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 7.5.2.1 | ATP + H2O + maltose/out | Salmonella enterica subsp. enterica serovar Typhimurium | translocation of maltose across biological membranes | ADP + phosphate + maltose/in | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 7.5.2.1 | Salmonella enterica subsp. enterica serovar Typhimurium | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 7.5.2.1 | purification of recombinant subunits | Salmonella enterica subsp. enterica serovar Typhimurium |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 7.5.2.1 | 1.25 | - |
- |
Salmonella enterica subsp. enterica serovar Typhimurium |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 7.5.2.1 | ATP + H2O + maltose/out | - |
Salmonella enterica subsp. enterica serovar Typhimurium | ADP + phosphate + maltose/in | - |
? | |
| 7.5.2.1 | ATP + H2O + maltose/out | translocation of maltose across biological membranes | Salmonella enterica subsp. enterica serovar Typhimurium | ADP + phosphate + maltose/in | - |
? | |
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