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Literature summary extracted from

  • Achouri, Y.; Noel, G.; Vertommen, D.; Rider, M.H.; Veiga-da-Cunha, M.; van Schaftingen, E.
    Identification of a dehydrogenase acting on D-2-hydroxyglutarate (2004), Biochem. J., 381, 35-42.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.99.2 (S)-2-hydroxyglutarate + acceptor Rattus norvegicus enzyme deficiency might be the cause of L-2-hydroxyglutaric aciduria 2-oxoglutarate + reduced acceptor
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 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.99.2 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.99.2 enzyme separated from D-2-hydroxyglutarate dehydrogenase by chromatography on DEAE-sepharose Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.99.2 liver
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 Rattus norvegicus
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.99.2 (S)-2-hydroxyglutarate + acceptor
-
 Rattus norvegicus 2-oxoglutarate + reduced acceptor
-
 ?
1.1.99.2 (S)-2-hydroxyglutarate + acceptor enzyme deficiency might be the cause of L-2-hydroxyglutaric aciduria Rattus norvegicus 2-oxoglutarate + reduced acceptor
-
 ?