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Literature summary extracted from

  • Tomitsuka, E.; Goto, Y.; Taniwaki, M.; Kita, K.
    Direct evidence for expression of type II flavoprotein subunit in human complex II (succinate-ubiquinone reductase) (2003), Biochem. Biophys. Res. Commun., 311, 774-779.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.3.5.1 cloning of 2 distinct cDNAs of flavoprotein subunit of SQR Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.3.5.1 atpenin A5 0.0000042 mM, 50% inhibition Homo sapiens
1.3.5.1 malonate 0.18 mM, 50% inhibition Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.3.5.1 mitochondrion
-
Homo sapiens 5739
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.3.5.1 succinate + ubiquinone Homo sapiens
-
fumarate + ubiquinol
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.3.5.1 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.3.5.1 brain expression of 2 distinct flavoprotein subunits Homo sapiens
-
1.3.5.1 heart expression of 2 distinct flavoprotein subunits Homo sapiens
-
1.3.5.1 HT-29 cell
-
Homo sapiens
-
1.3.5.1 kidney expression of 2 distinct flavoprotein subunits Homo sapiens
-
1.3.5.1 liver
-
Homo sapiens
-
1.3.5.1 liver expression of 2 distinct flavoprotein subunits Homo sapiens
-
1.3.5.1 RAJI cell express only type II Fp subunit of SQR complex Homo sapiens
-
1.3.5.1 skeletal muscle expression of 2 distinct flavoprotein subunits Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.3.5.1 0.024
-
SQR activity in raji cells Homo sapiens
1.3.5.1 0.039
-
SQR activity in HT-29 cells Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.5.1 succinate + ubiquinone
-
Homo sapiens fumarate + ubiquinol
-
?

Synonyms

EC Number Synonyms Comment Organism
1.3.5.1 complex II
-
Homo sapiens
1.3.5.1 SQR
-
Homo sapiens